Contact focusing multimodal microprobes for ultraprecise laser tissue surgery

被引：65

作者：

Darafsheh, Arash ^{[1
]}

Fardad, Amir ^{[2
]}

Fried, Nathaniel M. ^{[1
]}

Antoszyk, Andrew N. ^{[3
]}

Ying, Howard S. ^{[4
]}

Astratov, Vasily N. ^{[1
]}

机构：

[1] Univ N Carolina, Dept Phys & Opt Sci, Ctr Optoelect & Opt Commun, Charlotte, NC 28223 USA

[2] PhotonTech LLC, Res Triangle Pk, NC 27709 USA

[3] Charlotte Eye Ear Nose & Throat Associates, Retina Serv, Charlotte, NC 28210 USA

[4] Johns Hopkins Univ, Wilmer Eye Inst, Baltimore, MD 21287 USA

来源：

OPTICS EXPRESS | 2011年 / 19卷 / 04期

基金：

美国国家科学基金会;

关键词：

HOLLOW OPTICAL-FIBERS; ERBIUM-YAG LASER; DIELECTRIC MICROSPHERES; VITREORETINAL SURGERY; CLINICAL-EXPERIENCE; TRANSPORT PHENOMENA; PHOTONIC NANOJETS; SEALING CAPS; WAVE-GUIDES; CHAINS;

D O I：

10.1364/OE.19.003440

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Focusing of multimodal beams by chains of dielectric microspheres assembled directly inside the cores of hollow waveguides is studied by using numerical ray tracing. The device designs are optimized for laser surgery in contact mode with strongly absorbing tissue. By analyzing a broad range of parameters it is demonstrated that chains formed by three or five spheres with a refractive index of 1.65-1.75 provide a twofold improvement in spatial resolution over single spheres at the cost of 0.2-0.4 attenuation in peak intensity of the central focused beam. Potential applications include ultra precise laser ablation or coagulation in the eye and brain, cellular surgery, and the coupling of light into photonic nanostructures. (C) 2011 Optical Society of America

引用

页码：3440 / 3448

页数：9

共 38 条

[1] Optical-fiber-microsphere for remote fluorescence correlation spectroscopy [J].

Aouani, Heykel ;

Deiss, Frederique ;

Wenger, Jerome ;

Ferrand, Patrick ;

Sojic, Neso ;

Rigneault, Herve .

OPTICS EXPRESS, 2009, 17 (21) :19085-19092

[2]

Astratov V. N., 2011, International patent publication, Patent No. [WO/2011/005397, 2011005397]

[3]

Astratov V.N., 2010, SPIE NEWSROOM 0312

[4] Focus issue: Physics and applications of microresonators - Introduction [J].

Astratov, Vasily N. .

OPTICS EXPRESS, 2007, 15 (25) :17171-17171

[5]

Astratov VN, 2010, PR ELECTROMAGN RES S, P419

[6]

Astratov VN, 2010, SPRINGER SER OPT SCI, V156, P423, DOI 10.1007/978-1-4419-1744-7_17

[7] Optical coupling and transport phenomena in chains of spherical dielectric microresonators with size disorder [J].

Astratov, VN ;

Franchak, JP ;

Ashili, SP .

APPLIED PHYSICS LETTERS, 2004, 85 (23) :5508-5510

[8] Highly efficient optical coupling and transport phenomena in chains of dielectric microspheres [J].

Chen, ZG ;

Taflove, A ;

Backman, V .

OPTICS LETTERS, 2006, 31 (03) :389-391

[9] Photonic nanojet enhancement of backscattering of light by nanoparticles: a potential novel visible-light ultramicroscopy technique [J].

Chen, ZG ;

Taflove, A ;

Backman, V .

OPTICS EXPRESS, 2004, 12 (07) :1214-1220

[10] Analysis of scattering by a linear chain of spherical inclusions in an optical fiber [J].

Chremmos, Ioannis D. ;

Uzunoglu, Nikolaos K. .

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 2006, 23 (12) :3054-3062

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