Advances in Capillary Electrophoretically Mediated Microanalysis for On-line Enzymatic and Derivatization Reactions

被引:40
作者
Huang, Shengyun [1 ]
Paul, Prasanta [1 ]
Ramana, Pranov [1 ]
Adams, Erwin [1 ]
Augustijns, Patrick [2 ]
Van Schepdael, Ann [1 ]
机构
[1] KU Leuven Univ Leuven, Dept Pharmaceut & Pharmacol Sci, Pharmaceut Anal, Leuven, Belgium
[2] KU Leuven Univ Leuven, Dept Pharmaceut & Pharmacol Sci, Drug Delivery & Disposit, Leuven, Belgium
关键词
Capillary electrophoresis; Derivatization reactions; Electrophoretically mediated microanalysis; Immobilized enzyme reactors; On-line enzymatic analysis; TRADITIONAL CHINESE MEDICINES; LAMINAR-FLOW PROFILES; AMINO-ACIDS; TRANSVERSE DIFFUSION; POSTCOLUMN DERIVATIZATION; MAGNETIC NANOPARTICLES; ZONE-ELECTROPHORESIS; MATHEMATICAL-MODEL; PROTEIN DIGESTION; NATURAL EXTRACTS;
D O I
10.1002/elps.201700262
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This review summarizes recent developments, applications, and innovations of capillary electrophoretically mediated microanalysis methods. As a follow up of an earlier review, it covers the literature from early 2015 to early 2017. This article is divided into three parts. In the first part, different types of mixing procedures and applications of enzyme mediated microanalysis are discussed; the second part summarizes immobilized enzyme reactors (IMERs), while the third part deals with recent advances in on-line derivatization reactions.
引用
收藏
页码:97 / 110
页数:14
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