Vagus nerve stimulator treatment in adult-onset Rasmussen's encephalitis

被引：14

作者：

Grujic, Jelena ^{[2
]}

Bien, Christian G. ^{[3
]}

Pollo, Claudio ^{[2
,4
]}

Rossetti, Andrea O. ^{[1
,2
]}

机构：

[1] CHU Vaudois, Serv Neurol, CHUV BH07, Dept Clin Neurosci, CH-1011 Lausanne, Switzerland

[2] Univ Lausanne, CH-1015 Lausanne, Switzerland

[3] Univ Bonn Med Ctr, Dept Epileptol, Bonn, Germany

[4] CHU Vaudois, Serv Neurochirurg, Dept Clin Neurosci, CH-1011 Lausanne, Switzerland

来源：

EPILEPSY & BEHAVIOR | 2011年 / 20卷 / 01期

关键词：

Treatment; Epilepsy; Neuropsychological impairment; Partial status epilepticus; LONG-TERM; THERAPY; DIAGNOSIS; SEIZURES; EPILEPSY; CHILDREN; VARIANT; MOOD;

D O I：

10.1016/j.yebeh.2010.10.024

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

We describe a patient with adult-onset Rasmussen's encephalitis (RE) responsive to vagus nerve stimulation. This previously healthy woman developed RE in the right hemisphere at the age of 27. Despite antiepileptic drug polytherapy, she continued to experience subcontinuous, simple-partial left-sided motor seizures and slowly progressive cognitive impairment. Resective surgery was not considered owing to the preservation of left motor skills. She was implanted with a vagus nerve stimulator at the age of 41; after 6 months she experienced a greater than 50% reduction in seizure frequency, which persisted over 2 years together with improvement of her neurological and cognitive status. (C) 2010 Elsevier Inc. All rights reserved.

引用

页码：123 / 125

页数：3

共 13 条

[1] Astrocytes are a specific immunological target in Rasmussen's encephalitis [J].

Bauer, Jan ;

Eiger, Christian E. ;

Hans, Volkmar H. ;

Schramm, Johannes ;

Urbach, Horst ;

Lassmann, Hans ;

Bien, Christian G. .

ANNALS OF NEUROLOGY, 2007, 62 (01) :67-80

[2] Pathogenesis, diagnosis and treatment of Rasmussen encephalitis - A European consensus statement [J].

Bien, CG ;

Granata, T ;

Antozzi, C ;

Cross, JH ;

Dulac, O ;

Kurthen, M ;

Lassmann, H ;

Mantegazza, R ;

Villemure, JG ;

Spreafico, R ;

Elger, CE .

BRAIN, 2005, 128 :454-471

[3] Diagnosis and staging of Rasmussen's encephalitis by serial MRI and histopathology [J].

Bien, CG ;

Urbach, H ;

Deckert, M ;

Schramm, J ;

Wiestler, OD ;

Lassmann, H ;

Elger, CE .

NEUROLOGY, 2002, 58 (02) :250-257

[4] Treatment of Rasmussen encephalitis half a century after its initial description: Promising prospects and a dilemma [J].

Bien, Christian G. ;

Schramm, Johannes .

EPILEPSY RESEARCH, 2009, 86 (2-3) :101-112

[5] Prospective long-term study of vagus nerve stimulation for the treatment of refractory seizures [J].

DeGiorgio, CM ;

Schachter, SC ;

Handforth, A ;

Salinsky, M ;

Thompson, J ;

Uthman, B ;

Reed, R ;

Collins, S ;

Tecoma, E ;

Morris, GL ;

Vaughn, B ;

Naritoku, DK ;

Henry, T ;

Labar, D ;

Gilmartin, R ;

Labiner, D ;

Osorio, I ;

Ristanovic, R ;

Jones, J ;

Murphy, J ;

Ney, G ;

Wheless, J ;

Lewis, P ;

Heck, C .

EPILEPSIA, 2000, 41 (09) :1195-1200

[6] Limited chronic focal encephalitis - Another variant of Rasmussen syndrome? [J].

Gambardella, A. ;

Andermann, F. ;

Shorvon, S. ;

Le Piane, E. ;

Aguglia, U. .

NEUROLOGY, 2008, 70 (05) :374-377

[7] Vagus nerve stimulation in 15 children with therapy resistant epilepsy;: its impact on cognition, quality of life, behaviour and mood [J].

Hallböök, T ;

Lundgren, J ;

Stjernqvist, K ;

Blennow, G ;

Strömblad, LG ;

Rosén, M .

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2005, 14 (07) :504-513

[8] Chronic encephalitis and epilepsy in adults and adolescents: A variant of Rasmussen's syndrome? [J].

Hart, YM ;

Andermann, F ;

Fish, DR ;

Dubeau, F ;

Robitaille, Y ;

Rasmussen, T ;

Berkovic, S ;

Marino, R ;

Yakoubian, EM ;

Spillane, K ;

Scaravilli, F .

NEUROLOGY, 1997, 48 (02) :418-424

[9] Improvement in adult-onset Rasmussen's encephalitis with long-term immunomodulatory therapy [J].

Leach, JP ;

Chadwick, DW ;

Miles, JB ;

Hart, IK .

NEUROLOGY, 1999, 52 (04) :738-742

[10] The pathology of Rasmussen syndrome: Stages of cortical involvement and neuropathological studies in 45 hemispherectomies [J].

Pardo, CA ;

Vining, EPG ;

Guo, L ;

Skolasky, RL ;

Carson, BS ;

Freeman, JM .

EPILEPSIA, 2004, 45 (05) :516-526

← 1 2 →