Serum α-fetoprotein screening for hepatoblastoma in children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia

被引：66

作者：

Clericuzio, CL

Chen, E

McNeil, DE

O'Connor, T

Zackai, EH

Medne, L

Tomlinson, G

DeBaun, M

机构：

[1] Univ New Mexico, Dept Pediat, Albuquerque, NM 87131 USA

[2] Childrens Hosp Oakland, Res Inst, Oakland, CA USA

[3] NCI, Genet Epidemiol Branch, Bethesda, MD 20892 USA

[4] Childrens Hosp Philadelphia, Dept Pediat, Philadelphia, PA 19104 USA

[5] Univ Texas SW, Dept Pediat, Dallas, TX 75235 USA

[6] Boone Cty Hosp, Dept Pediat, Columbia, MO USA

[7] Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA

来源：

JOURNAL OF PEDIATRICS | 2003年 / 143卷 / 02期

关键词：

D O I：

10.1067/S0022-3476(03)00306-8

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

An elevated risk of hepatoblastoma for children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia is well established. We describe five children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia for whom serial serum alpha-fetoprotein screening, usually in combination with abdominal ultrasound, led to early detection of hepatoblastoma.

引用

页码：270 / 272

页数：3

共 13 条

[1]

Choyke PL, 1999, MED PEDIATR ONCOL, V32, P196, DOI 10.1002/(SICI)1096-911X(199903)32:3<196::AID-MPO6>3.0.CO

[2]

2-9

[3]

Clericuzio CL, 1999, AM J MED GENET, V89, P81, DOI 10.1002/(SICI)1096-8628(19990625)89:2<81::AID-AJMG5>3.0.CO

[4]

2-I

[5] Risk of cancer during the first four years of life in children from The Beckwith-Wiedemann Syndrome Registry [J].

DeBaun, MR ;

Tucker, MA .

JOURNAL OF PEDIATRICS, 1998, 132 (03) :398-400

[6]

ELIAS ER, 1998, PRINCIPLES MOL MED, P1047

[7] Serum α-fetoprotein levels in Beckwith-Wiedemann syndrome [J].

Everman, DB ;

Shuman, C ;

Dzolganovski, B ;

O'Riordan, MA ;

Weksberg, R ;

Robin, NH .

JOURNAL OF PEDIATRICS, 2000, 137 (01) :123-127

[8]

Hoyme HE, 1998, AM J MED GENET, V79, P274, DOI 10.1002/(SICI)1096-8628(19981002)79:4<274::AID-AJMG8>3.3.CO

[9]

2-K

[10] BIPHASIC REDUCTION AND CONCANAVALIN-A BINDING-PROPERTIES OF SERUM ALPHA-FETOPROTEIN IN PRETERM AND TERM INFANTS [J].

LAHDENNE, P ;

KUUSELA, P ;

SIIMES, MA ;

RONNHOLM, KAR ;

SALMENPERA, L ;

HEIKINHEIMO, M .

JOURNAL OF PEDIATRICS, 1991, 118 (02) :272-276

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