Treatment of Basal Cell Carcinoma in the Elderly: What Nondermatologists Need to Know

被引:12
作者
Wiznia, Lauren E. [1 ]
Federman, Daniel G. [2 ]
机构
[1] NYU, Sch Med, Ronald O Perelman Dept Dermatol, 240 East 38th St,11th Floor, New York, NY 10016 USA
[2] Yale Univ, Sch Med, VA Connecticut Healthcare Syst, West Haven, CT 06516 USA
关键词
Basal cell carcinoma; Cryosurgery; Dermatologic surgery; Elderly; Electrodessication and curettage; Imiquimod; Life expectancy; Mohs surgery; Nonmelanoma skin cancer; Photodynamic therapy; Vismodegib; MOHS MICROGRAPHIC SURGERY; NONMELANOMA SKIN-CANCER; AGED; 90; YEARS; PHOTODYNAMIC THERAPY; TREATMENT MODALITIES; SURGICAL EXCISION; LIFE EXPECTANCY; MANAGEMENT; CURETTAGE; END;
D O I
10.1016/j.amjmed.2016.03.003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
As the population ages and incidence of basal cell carcinoma continues to increase, we will be faced more frequently with difficult treatment decisions for basal cell carcinoma in the elderly. Different treatment options, including surgical excision, electrodessication and curettage, cryosurgery, imiquimod, photodynamic therapy, 5-fluorouracil, radiation therapy, vismodegib, combination therapy, and observation, may be considered on the basis of tumor characteristics. Given the wide range of therapeutic options, treatments can be tailored to achieve patients' goals of care within their anticipated life expectancy. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码:655 / 660
页数:6
相关论文
共 42 条
[1]   Basal cell carcinoma of the face: Surgery or radiotherapy? Results of a randomized study [J].
Avril, MF ;
Auperin, A ;
Margulis, A ;
Gerbaulet, A ;
Duvillard, P ;
Benhamou, E ;
Guillaume, JC ;
Chalon, R ;
Petit, JY ;
SanchoGarnier, H ;
Prade, M ;
Bouzy, J ;
Chassagne, D .
BRITISH JOURNAL OF CANCER, 1997, 76 (01) :100-106
[2]   Interventions for preventing non-melanoma skin cancers in high-risk groups [J].
Bath-Hextall, F. ;
Leonardi-Bee, J. ;
Somchand, N. ;
Webster, A. ;
Delitt, J. ;
Perkins, W. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2007, (04)
[3]   Facial basal cell carcinoma [J].
Baxter, Julia M. ;
Patel, Anand N. ;
Varma, Sandeep .
BMJ-BRITISH MEDICAL JOURNAL, 2012, 345
[4]  
Bolognia JL., 2012, BOLOGNIA TXB DERMATO, V3rd ed., DOI DOI 10.1016/J.PIEL.2013.01.001
[5]  
Burkhart CN., 2012, FITZPATRICKS DERMATO, P2571
[6]   Current modalities and new advances in the treatment of basal cell carcinoma [J].
Ceilley, RI ;
Del Rosso, JQ .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 2006, 45 (05) :489-498
[7]  
Centers for Disease Control and Prevention (CDC), 2003, MMWR Morb Mortal Wkly Rep, V52, P106
[8]  
Centers for Disease Control and Prevention (CDC), 2003, MMWR Morb Mortal Wkly Rep, V52, P101
[9]   Prognostic factors for life expectancy in nonagenarians with nonmelanoma skin cancer: Implications for selecting surgical candidates [J].
Charles, AJ ;
Otley, CC ;
Pond, GR .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2002, 47 (03) :419-422
[10]   Superficial x-ray in the treatment of basal and squamous cell carcinomas: A viable option in select patients [J].
Cognetta, Armand B. ;
Howard, Brett M. ;
Heaton, Henry P. ;
Stoddard, Earl R. ;
Hong, Hyokyoung Grace ;
Green, W. Harris .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2012, 67 (06) :1235-1241