One-pot synthesis of substituted dibenzoxazepinones and pyridobenzoxazepinones using octacarbonyldicobalt as an effective CO source

被引：3

作者：

Anchan, Kavitha ^{[1
,2
]}

Baburajan, Poongavanam ^{[2
]}

Puttappa, Nagaswarupa H. ^{[3
]}

Kumar Sarkar, Sujit ^{[2
]}

机构：

[1] Bharathiar Univ, Res & Dev Ctr, Coimbatore, Tamil Nadu, India

[2] Syngene Int Ltd, Discovery Chem, Bangalore, Karnataka, India

[3] Davangere Univ, PG Dept Chem, Davangere, India

来源：

SYNTHETIC COMMUNICATIONS | 2020年 / 50卷 / 03期

关键词：

Amidation; Co-2(CO)8; dibenzoxazepinones; intramolecular cyclization; pyridobenzoxazepinones; BINDING; FUNCTIONALIZATION; DERIVATIVES; NITROGEN;

D O I：

10.1080/00397911.2019.1695277

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile one-pot protocol for the synthesis of substituted dibenzoxazepinones and pyridobenzoxazepinones from commercially available aryl/heteroaryl halides and amino phenols using octacarbonyldicobalt (Co-2(CO)(8)) as an effective metal carbonyl source has been demonstrated. This method proceeds via the sequential coupling of aryl/heteroaryl halides with aminophenol by amidation and intramolecular cyclization to give dibenzoxazepinones/pyridobenzoxazepinones.

引用

页码：348 / 360

页数：13

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