Fully automated whole-body registration in mice using an articulated skeleton atlas

被引:16
作者
Baiker, M. [1 ,2 ]
Milles, J. [1 ]
Vossepoell, A. M. [2 ]
Que, I.
Kaijzel, E. L. [3 ]
Lowik, C. W. G. M. [3 ]
Reiber, J. H. C. [1 ]
Dykstra, J. [1 ]
Lelieveldt, B. P. F. [1 ]
机构
[1] Leiden Univ, Med Ctr, Dept Radiol, Div Image Proc, NL-2300 RA Leiden, Netherlands
[2] Delft Univ Technol, Quantitative Imag Grp, Delft, Netherlands
[3] Leiden Univ Med, Dept Endocrinol, Leiden, Netherlands
来源
2007 4TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING : MACRO TO NANO, VOLS 1-3 | 2007年
关键词
articulated registration; Micro-CT; atlas-based matching;
D O I
10.1109/ISBI.2007.356955
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
In this paper, we propose a fully automated articulated registration approach for whole-body 3D data of mice. The method is based on a hierarchical anatomical model of the skeletal system where we specified position and degrees of freedom for each joint. Model fitting is performed by traversing a hierarchical part-tree, which enables a coarse-to-fine registration from the inner articulations outwards. The method was tested on 12 Micro-CT volumes, giving accurate alignment of the skeletal structures in all cases.
引用
收藏
页码:728 / +
页数:2
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