A new Butenolide Derivative from the Brown Alga Sargassum micracanthum

被引:1
作者
Kim, Ji-Yul [1 ]
Lee, Jeong Min [1 ]
Kim, Hyun-Soo [1 ]
Ki, Dae-Won [2 ,3 ]
Yim, Mi-Jin [1 ]
Ko, Seok-Chun [1 ]
Shin, Jung Min [1 ]
Lee, Myeong Seok [1 ]
Park, Yun Gyeong [1 ]
Lee, Dae-Sung [1 ]
机构
[1] Natl Marine Biodivers Inst Korea, Dept Genet Resources Res, Seocheon, South Korea
[2] Jeonbuk Natl Univ, Coll Environm & Bioresource Sci, Div Biotechnol, Iksan Si, South Korea
[3] Jeonbuk Natl Univ, Coll Environm & Bioresource Sci, Adv Inst Environm & Biosci, Iksan Si, South Korea
关键词
butenolide; brown alga; NMR; Sargassum micracanthum; FARNESYLACETONE DERIVATIVES; PLASTOQUINONES; ANTIOXIDANT;
D O I
10.1177/1934578X211068606
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new butenolide derivative (1), along with three known compounds (2-4) were isolated from the MeOH extract of brown alga Sargassum micracanthum. The structures of 1 to 4 were determined by the analyses of 1D and 2D NMR and mass spectroscopic data. The known compounds (2-4) were identified as (5E,10Z)-6,10,14-trimethylpentadeca-5,10-dien-2,12-dione (2), (5E,9E)-6,10,14-trimethylpentadeca-5,9-dien-2,12-dione (3), and (-)-loliolide (4) by comparing with their published spectroscopic data. The antioxidant activities of compounds 1 to 4 were evaluated based on using 2,2 '-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities. Compounds 1 to 4 were inactive at the concentration of 200 mu M.
引用
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页数:4
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