MASTERKEY-265: A phase III, randomized, placebo (Pbo)-controlled study of talimogene laherparepvec (T) plus pembrolizumab (P) for unresectable stage IIIB-IVM1c melanoma (MEL)

被引:33
作者
Ribas, A. [1 ]
Chesney, J. [2 ]
Long, G. V. [3 ]
Kirkwood, J. M. [4 ]
Dummer, R. [5 ]
Puzanov, I. [6 ]
Hoeller, C. [7 ]
Gajewski, T. F. [8 ]
Gutzmer, R. [9 ]
Rutkowski, P. [10 ]
Demidov, L. [11 ]
Arenberger, P. [12 ]
Shin, S. J. [13 ]
Ferrucci, P. F. [14 ]
Diede, S. J. [15 ]
Anderson, J. R. [16 ]
Treichel, S. [17 ]
Chan, E. [17 ]
Hodi, F. S. [18 ]
Gogas, H. J. [19 ]
机构
[1] Univ Calif Los Angeles, Dept Med, Jonsson Comprehens Canc Ctr, Los Angeles, CA USA
[2] Brown Canc Ctr Univ Louisville, Dept Med Hematol Oncol, Biochem Mol Biol & Pharmacol Toxicol, Louisville, KY USA
[3] Melanoma Inst Australia, Melanoma Med Oncol Translat Res, Wollstonecraft, NSW, Australia
[4] UPMC Hillman Canc Ctr, Melanoma Program, Pittsburgh, PA USA
[5] Univ Zurich, Dept Dermatol, Klin Dermatol, Zurich, Switzerland
[6] Roswell Pk Comprehens Canc Ctr, Dept Med, Buffalo, NY USA
[7] Med Univ Wien, Dept Dermatol & Dermatooncol, Vienna, Austria
[8] Univ Chicago, Ben May Dept Canc Res & Dept Pathol, Chicago, IL USA
[9] Hannover Med Sch, Dermatol Skin Canc Ctr, Dermatol Klin, Hannover, Germany
[10] Maria Sklodowska Curie Natl Res Inst Oncol, Dept Soft Tissue Bone Sarcoma & Melanoma, Warsaw, Poland
[11] NN Blokhin Russian Canc Res Ctr, Ctr Canc, Moscow, Russia
[12] Univ Hosp Kralovske Vinohrady, Dermatovenereol Clin, Prague, Czech Republic
[13] Yonsei Univ, Severance Hosp, Coll Med, Seoul, South Korea
[14] IEO Ist Europeo Oncol, Dept Oncol, Milan, Italy
[15] Merck Co & Inc, Oncol Clin Res, MRL Labs, Upper Gwynedd Campus, North Wales, PA USA
[16] Merck & Co Inc, BARDS, Upper Gwynedd Site, North Wales, PA USA
[17] Amgen Headquarters USA, Amgen Ctr Dr, Thousand Oaks, CA USA
[18] Dana Farber Canc Inst, Melanoma Ctr, Boston, MA USA
[19] Natl & Kapodistrian Univ Athens, Med, Athens, Greece
关键词
D O I
10.1016/j.annonc.2021.08.1422
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1037O
引用
收藏
页码:S868 / S869
页数:2
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