Epigenetic mechanisms are involved in the cytokine-induced de novo expression of IL-1 beta in human articular chondrocytes in vitro

被引:0
|
作者
Hashimoto, K. [1 ]
Kokubun, S. [1 ]
Itoi, E. [1 ]
Roach, H. I. [2 ]
机构
[1] Tohoku Univ, Dept Orthopaed, Sendai, Miyagi, Japan
[2] Univ Southampton, Bone & Joint Res Grp, Southampton, Hants, England
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
M184
引用
收藏
页码:S168 / S168
页数:1
相关论文
共 50 条
  • [41] IL-1β and TNF-α alter the glycophenotype of primary human chondrocytes in vitro
    Pabst, Martin
    Wu, Shengqian Q.
    Grass, Josephine
    Kolb, Alexander
    Chiari, Catharina
    Viernstein, Helmut
    Unger, Frank M.
    Altmann, Friedrich
    Toegel, Stefan
    CARBOHYDRATE RESEARCH, 2010, 345 (10) : 1389 - 1393
  • [42] TNF-ALPHA AND IL-1 ACT SYNERGISTICALLY IN THE INDUCTION OF IL-8 IN HUMAN ARTICULAR CHONDROCYTES
    RECKLIES, AD
    BAILLARGEON, L
    ARTHRITIS AND RHEUMATISM, 1992, 35 (09): : S122 - S122
  • [43] IL-1-BETA-INDUCED EXPRESSION OF PDGF-AA ISOFORM IN RABBIT ARTICULAR CHONDROCYTES IS MODULATED BY TGF-BETA-1
    PERACCHIA, F
    FERRARI, G
    POGGI, A
    ROTILIO, D
    EXPERIMENTAL CELL RESEARCH, 1991, 193 (01) : 208 - 212
  • [44] Matrine inhibits IL-1β-induced expression of matrix metalloproteinases by suppressing the activation of MAPK and NF-κB in human chondrocytes in vitro
    Lu, Shijin
    Xiao, Xungang
    Cheng, Minghua
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2015, 8 (05): : 4764 - 4772
  • [45] Human endothelial senescence induced by IL-1α in vitro
    Yao, AY
    Zhou, JJ
    Liu, YB
    Feng, MF
    Zhou, RL
    PROGRESS IN NATURAL SCIENCE-MATERIALS INTERNATIONAL, 2004, 14 (03) : 218 - 222
  • [46] Human endothelial senescence induced by IL-1α in vitro
    YAO Aiyu 1
    2. Department of Cell Biology and Medical Genetics
    ProgressinNaturalScience, 2004, (03) : 26 - 30+97
  • [47] IL-1 PREFERENTIALLY STIMULATES THE PRODUCTION OF A TISSUE PLASMINOGEN-ACTIVATOR BY HUMAN ARTICULAR CHONDROCYTES
    BUNNING, RAD
    CRAWFORD, A
    RICHARDSON, HJ
    OPDENAKKER, G
    CEDERHOLMWILLIAMS, SA
    DINARELLO, CA
    RUSSELL, RGG
    CALCIFIED TISSUE INTERNATIONAL, 1986, 38 (NS) : S33 - S33
  • [48] Inflammatory cytokines have the capacity to de-methylate specific CpG sites in the promoter of IL-1β, which underlies induction of abnormal expression in healthy human articular chondrocytes in-vitro
    Hashimoto, K.
    Kokubun, S.
    Itoi, E.
    Roach, H. I.
    INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 2009, 90 (02) : A99 - A100
  • [49] Peroxisome proliferator-activated receptor gamma 1 expression is diminished in human osteoarthritis cartilage and is downregulated by IL-1β in articular chondrocytes
    Afif, H.
    Mfuna, L.
    Martel-Pelletier, J.
    Pelletier, J-P
    Fahmi, H.
    ARTHRITIS RESEARCH & THERAPY, 2007, 9 (Suppl 3)
  • [50] Peroxisome proliferator-activated receptor gamma 1 expression is diminished in human osteoarthritis cartilage and is downregulated by IL-1β in articular chondrocytes
    H Afif
    L Mfuna
    J Martel-Pelletier
    J-P Pelletier
    H Fahmi
    Arthritis Research & Therapy, 9