Total Thyroidectomy Versus Lobectomy for the Treatment of Follicular Thyroid Microcarcinoma

被引：0

作者：

Megwalu, Uchechukwu C. ^{[1
]}

Green, Ross W. ^{[2
]}

机构：

[1] Stanford Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, 801 Welch Rd, Stanford, CA 94305 USA

[2] Icahn Sch Med Mt Sinai, Dept Otolaryngol Head & Neck Surg, New York, NY 10029 USA

来源：

ANTICANCER RESEARCH | 2016年 / 36卷 / 06期

关键词：

SEER database; thyroid cancer; microcarcinoma; thyroidectomy; propensity score; comparative effectiveness; PAPILLARY; SURVIVAL;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Aim: To compare the effectiveness of total thyroidectomy versus thyroid lobectomy for the treatment of follicular thyroid microcarcinoma. Patients and Methods: Data were extracted from the Surveillance, Epidemiology, and End Results 18 Database. The study cohort included patients diagnosed with follicular thyroid microcarcinoma between 1988 and 2009, treated with either total thyroidectomy or thyroid lobectomy. Propensity-score analysis using inverse probability weighting was used to control for allocation bias. Results: A total of 203 patients were identified. The 5-year overall survival was 98% for patients treated with lobectomy and 99% for those treated with total thyroidectomy; this difference was not statistically significant (p=0.13). Unadjusted analysis and propensity-score analysis revealed no difference in overall survival between the two treatment groups (p=0.15 and p=0.49, respectively). Conclusion: Total thyroidectomy does not appear to offer any survival advantage over thyroid lobectomy for patients with follicular thyroid microcarcinoma.

引用

页码：2899 / 2902

页数：4

共 11 条

[1] Total versus hemithyroidectomy for microscopic papillary thyroid cancer [J].

Gershinsky, M. ;

Barnett-Griness, O. ;

Stein, N. ;

Hirsch, D. ;

Tzvetov, G. ;

Bardicef, O. ;

Pauker, J. ;

Grozinsky-Glasberg, S. ;

Ish-Shalom, S. ;

Slutski, I. ;

Shimon, I. ;

Benbassat, C. .

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 2012, 35 (05) :464-468

[2] 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer [J].

Haugen, Bryan R. ;

Alexander, Erik K. ;

Bible, Keith C. ;

Doherty, Gerard M. ;

Mandel, Susan J. ;

Nikiforov, Yuri E. ;

Pacini, Furio ;

Randolph, Gregory W. ;

Sawka, Anna M. ;

Schlumberger, Martin ;

Schuff, Kathryn G. ;

Sherman, Steven I. ;

Sosa, Julie Ann ;

Steward, David L. ;

Tuttle, R. Michael ;

Wartofsky, Leonard .

THYROID, 2016, 26 (01) :1-133

[3]

Howlader N, 2016, SEER CANC STAT REV 1

[4] The Most Commonly Occurring Papillary Thyroid Cancer in the United States Is Now a Microcarcinoma in a Patient Older than 45 Years [J].

Hughes, David T. ;

Haymart, Megan R. ;

Miller, Barbra S. ;

Gauger, Paul G. ;

Doherty, Gerard M. .

THYROID, 2011, 21 (03) :231-236

[5] Patients with follicular and Hurthle cell microcarcinomas have compromised survival: A population level study of 22,738 patients [J].

Kuo, Eric J. ;

Roman, Sanziana A. ;

Sosa, Julie A. .

SURGERY, 2013, 154 (06) :1246-1253

[6] Long-Term Outcomes of Total Thyroidectomy Versus Thyroid Lobectomy for Papillary Thyroid Microcarcinoma: Comparative Analysis After Propensity Score Matching [J].

Lee, Jandee ;

Park, Jae Hyun ;

Lee, Cho-Rok ;

Chung, Woong Youn ;

Park, Cheong Soo .

THYROID, 2013, 23 (11) :1408-1415

[7] Survival Impact of Treatment Options for Papillary Microcarcinoma of the Thyroid [J].

Lin, Harrison W. ;

Bhattacharyya, Neil .

LARYNGOSCOPE, 2009, 119 (10) :1983-1987

[8] Matching using estimated propensity scores: Relating theory to practice [J].

Rubin, DB ;

Thomas, N .

BIOMETRICS, 1996, 52 (01) :249-264

[9] Estimating causal effects from large data sets using propensity scores [J].

Rubin, DB .

ANNALS OF INTERNAL MEDICINE, 1997, 127 (08) :757-763

[10] Papillary Thyroid Microcarcinoma: An Over-Treated Malignancy? [J].

Wang, Tracy S. ;

Goffredo, Paolo ;

Sosa, Julie Ann ;

Roman, Sanziana A. .

WORLD JOURNAL OF SURGERY, 2014, 38 (09) :2297-2303

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