Essential tremor: Phenotypic expression in a clinical cohort

被引：77

作者：

Whaley, N. R. ^{[1
]}

Putzke, John D. ^{[1
]}

Baba, Yasuhiko ^{[1
]}

Wszolek, Zbigniew K. ^{[1
]}

Uitti, Ryan J. ^{[1
]}

机构：

[1] Mayo Clin, Dept Neurol, Jacksonville, FL 32225 USA

来源：

PARKINSONISM & RELATED DISORDERS | 2007年 / 13卷 / 06期

关键词：

essential tremor; clinical features; phenotype;

D O I：

10.1016/j.parkreldis.2006.12.004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objectives: Examine the characteristics of an essential tremor (ET) clinical cohort including base-rate variability of several commonly accepted diagnostic criteria. Methods: A clinical series of 487 consecutive individuals diagnosed with ET were included for study. Results: The sample was 53% male, had a mean age of onset of 52, and a mean age of 71. Half of the sample had a family history of ET. Half presented with asymmetrical disease and tremor affected the arms (97%), voice (62%), and head or neck (48%). There was considerable variability in the base rate of individuals fulfilling various commonly used diagnostic criteria of ET. Conclusion: The sample was deemed representative of ET clinical cohorts. Asymmetric disease was common, and there was considerable base-rate variation across traditional ET diagnostic criteria. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：333 / 339

页数：7

共 43 条

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