Highly Effective Pd-Catalyzed ortho Olefination of Acetanilides: Broad Substrate Scope and High Tolerability

被引：58
作者：
Kim, Byung Seok [1 ]
Jang, Chungsik [2 ]
Lee, Dong Jin [1 ]
Youn, So Won [1 ]
机构：
[1] Hanyang Univ, Dept Chem, Seoul 133791, South Korea
[2] Pukyong Natl Univ, Dept Chem, Pusan, South Korea
来源：
CHEMISTRY-AN ASIAN JOURNAL | 2010年 / 5卷 / 11期
基金：
新加坡国家研究基金会;
关键词：
acetanilides; C-H activation; olefination; palladium; C-H ACTIVATION; CROSS-COUPLING REACTIONS; N BOND FORMATION; DIRECT ARYLATION; SIMPLE ARENES; FUNCTIONALIZATION; REACTIVITY; ANILIDES; CARBON; PALLADIUM(II);
D O I：
10.1002/asia.201000613
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Bring it on! An effective Pd-catalyzed ortho olefination of various acetanilides has been developed. This transformation has a broad substrate scope and wide functional-group tolerability, regardless of the electronic and steric properties of acetanilide substrates, providing a straightforward access to highly functionalized arenes. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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收藏
页码：2336 / 2340
页数：5
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