Crystal structure and antibacterial evaluation of epifriedelinol isolated from Vitex peduncularis Wall. ex Schauer

被引：13

作者：

Kannathasan, K. ^{[1
]}

Senthilkumar, A. ^{[1
]}

Venkatesalu, V. ^{[1
]}

机构：

[1] Annamalai Univ, Dept Bot, Annamalainagar 608002, Tamil Nadu, India

来源：

ARABIAN JOURNAL OF CHEMISTRY | 2019年 / 12卷 / 08期

关键词：

Vitex peduncularis; Epifriedelinol; Antibacterial; Crystal structure;

D O I：

10.1016/j.arabjc.2015.02.013

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Epifriedelinol, an antibacterial pentacyclic triterpene was isolated from the methanol extract of Vitex peduncularis by bio-assay guided separation and the structure of the compound was elucidated by various spectroscopic methods such as H-1 NMR, C-13 NMR and single crystal X-ray Diffraction. The antibacterial activity of epifriedelinol was examined against five species of Gram positive and seven strains of Gram negative bacteria. The presence of epifriedelinol in V. peduncularis and its antibacterial activity were reported for the first time. (C) 2015 The Authors. Published by Elsevier B.V. on behalf of King Saud University.

引用

页码：2289 / 2292

页数：4

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