Intravenous thrombolysis for acute ischemic stroke

被引：14

作者：

Turc, G. ^{[1
,2
,3
]}

Isabel, C. ^{[1
,2
]}

Calvet, D. ^{[1
,2
,3
]}

机构：

[1] St Anne Hosp, Stroke Unit, F-75014 Paris, France

[2] Univ Paris 05, Sorbonne Paris Cite, Paris, France

[3] INSERM, UMR S894, F-75654 Paris 13, France

来源：

DIAGNOSTIC AND INTERVENTIONAL IMAGING | 2014年 / 95卷 / 12期

关键词：

Stroke; Ischemia; Thrombolysis; Interventional radiology; Thrombectomy; TISSUE-PLASMINOGEN ACTIVATOR; SYMPTOM ONSET; WAKE-UP; TIME; RECANALIZATION; ALTEPLASE; TRIAL; HEMORRHAGE; MINUTES; THERAPY;

D O I：

10.1016/j.diii.2014.10.002

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Intravenous thrombolysis ( IVT) with alteplase remains the standard treatment for acute ischemic stroke. Although IVT can be started up to 4.5 hours after symptoms' onset, it is all the more effective and safe when started early. It allows a 10% absolute reduction in the risk of handicap or death at 3 months, despite a 2- 7% risk of symptomatic intracranial hemorrhage. Current research efforts involve firstly trying to treat a larger proportion of patients by over-coming some of the contraindications to IVT and secondly assessing combined or alternative treatments to achieve a higher early recanalization rate.(C) 2014 editions francaises de radiologie.Published by Elsevier Masson SAS. All rights reserved.

引用

页码：1129 / 1133

页数：5

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