A systematic strategy for preparation of uncommon sugars through enzymatic resolution and ring-closing metathesis

被引：27

作者：

Zhu, LH ^{[1
]}

Kedenburg, JP ^{[1
]}

Xian, M ^{[1
]}

Wang, PG ^{[1
]}

机构：

[1] Ohio State Univ, Dept Biochem, Columbus, OH 43210 USA

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 05期

基金：

美国国家科学基金会;

关键词：

uncommon sugars; enzymatic resolution; ring-closing metathesis;

D O I：

10.1016/j.tetlet.2004.12.014

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A systematic synthetic strategy has been developed for producing uncommon sugars. This method involved kinetic resolution allylic alcohol followed by ring-closing-metathesis (RCM) to generate optical pure lactones as the common precursors. After further derivatization, four representative uncommon sugar units were successfully synthesized. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：811 / 813

页数：3

共 25 条

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