Genetic biomarker for cancer immunotherapy

被引:8
作者
Goswami, Sangeeta [1 ]
Sharma, Padmanee [1 ,2 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Genitourinary Med Oncol, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Immunol, Houston, TX 77030 USA
关键词
CTLA-4; BLOCKADE; COLORECTAL-CANCER; PD-1; LANDSCAPE; MELANOMA;
D O I
10.1126/science.aao1894
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:358 / 358
页数:1
相关论文
共 14 条
  • [1] ESHLEMAN JR, 1995, ONCOGENE, V10, P33
  • [2] Lessons from hereditary colorectal cancer
    Kinzler, KW
    Vogelstein, B
    [J]. CELL, 1996, 87 (02) : 159 - 170
  • [3] PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
    Le, D. T.
    Uram, J. N.
    Wang, H.
    Bartlett, B. R.
    Kemberling, H.
    Eyring, A. D.
    Skora, A. D.
    Luber, B. S.
    Azad, N. S.
    Laheru, D.
    Biedrzycki, B.
    Donehower, R. C.
    Zaheer, A.
    Fisher, G. A.
    Crocenzi, T. S.
    Lee, J. J.
    Duffy, S. M.
    Goldberg, R. M.
    de la Chapelle, A.
    Koshiji, M.
    Bhaijee, F.
    Huebner, T.
    Hruban, R. H.
    Wood, L. D.
    Cuka, N.
    Pardoll, D. M.
    Papadopoulos, N.
    Kinzler, K. W.
    Zhou, S.
    Cornish, T. C.
    Taube, J. M.
    Anders, R. A.
    Eshleman, J. R.
    Vogelstein, B.
    Diaz, L. A., Jr.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (26) : 2509 - 2520
  • [4] Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
    Le, Dung T.
    Durham, Jennifer N.
    Smith, Kellie N.
    Wang, Hao
    Bartlett, Bjarne R.
    Aulakh, Laveet K.
    Lu, Steve
    Kemberling, Holly
    Wilt, Cara
    Luber, Brandon S.
    Wong, Fay
    Azad, Nilofer S.
    Rucki, Agnieszka A.
    Laheru, Dan
    Donehower, Ross
    Zaheer, Atif
    Fisher, George A.
    Crocenzi, Todd S.
    Lee, James J.
    Greten, Tim F.
    Duffy, Austin G.
    Ciombor, Kristen K.
    Eyring, Aleksandra D.
    Lam, Bao H.
    Joe, Andrew
    Kang, S. Peter
    Holdhoff, Matthias
    Danilova, Ludmila
    Cope, Leslie
    Meyer, Christian
    Zhou, Shibin
    Goldberg, Richard M.
    Armstrong, Deborah K.
    Bever, Katherine M.
    Fader, Amanda N.
    Taube, Janis
    Housseau, Franck
    Spetzler, David
    Xiao, Nianqing
    Pardoll, Drew M.
    Papadopoulos, Nickolas
    Kinzler, Kenneth W.
    Eshleman, James R.
    Vogelstein, Bert
    Anders, Robert A.
    Diaz, Luis A., Jr.
    [J]. SCIENCE, 2017, 357 (6349) : 409 - 413
  • [5] Enhancement of antitumor immunity by CTLA-4 blockade
    Leach, DR
    Krummel, MF
    Allison, JP
    [J]. SCIENCE, 1996, 271 (5256) : 1734 - 1736
  • [6] Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
    Rizvi, Naiyer A.
    Hellmann, Matthew D.
    Snyder, Alexandra
    Kvistborg, Pia
    Makarov, Vladimir
    Havel, Jonathan J.
    Lee, William
    Yuan, Jianda
    Wong, Phillip
    Ho, Teresa S.
    Miller, Martin L.
    Rekhtman, Natasha
    Moreira, Andre L.
    Ibrahim, Fawzia
    Bruggeman, Cameron
    Gasmi, Billel
    Zappasodi, Roberta
    Maeda, Yuka
    Sander, Chris
    Garon, Edward B.
    Merghoub, Taha
    Wolchok, Jedd D.
    Schumacher, Ton N.
    Chan, Timothy A.
    [J]. SCIENCE, 2015, 348 (6230) : 124 - 128
  • [7] Neoantigens in cancer immunotherapy
    Schumacher, Ton N.
    Schreiber, Robert D.
    [J]. SCIENCE, 2015, 348 (6230) : 69 - 74
  • [8] Epitope landscape in breast and colorectal cancer
    Segal, Neil H.
    Parsons, D. Williams
    Peggs, Karl S.
    Velcutlescu, Victor
    Kinzler, Ken W.
    Vogelstein, Bert
    Allison, James P.
    [J]. CANCER RESEARCH, 2008, 68 (03) : 889 - 892
  • [9] The future of immune checkpoint therapy
    Sharma, Padmanee
    Allison, James P.
    [J]. SCIENCE, 2015, 348 (6230) : 56 - 61
  • [10] Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
    Snyder, Alexandra
    Makarov, Vladimir
    Merghoub, Taha
    Yuan, Jianda
    Zaretsky, Jesse M.
    Desrichard, Alexis
    Walsh, Logan A.
    Postow, Michael A.
    Wong, Phillip
    Ho, Teresa S.
    Hollmann, Travis J.
    Bruggeman, Cameron
    Kannan, Kasthuri
    Li, Yanyun
    Elipenahli, Ceyhan
    Liu, Cailian
    Harbison, Christopher T.
    Wang, Lisu
    Ribas, Antoni
    Wolchok, Jedd D.
    Chan, Timothy A.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (23) : 2189 - 2199