Radical deoxygenation of 3-azatricyclo[2.2.1.02,6]heptan-5-ols to 1,2-dihydropyridines

被引：6

作者：

Hodgson, DM ^{[1
]}

Jones, ML

Maxwell, CR

Ichihara, O

Matthews, IR

机构：

[1] Univ Oxford, Dept Chem, Chem Res Lab, Oxford OX1 3TA, England

[2] Evotec OAI, Abingdon OX14 4SD, Oxon, England

来源：

SYNLETT | 2005年 / 02期

关键词：

free radicals; deoxygenation; rearrangements; alcohols; dihydropyridines;

D O I：

10.1055/s-2004-836066

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Radical deoxygenations of 7-alkyl-1-tosyl-3-azatricyclo[2.2. 1.0(2,6)]heptan-5-ols 9 (R = alkyl) give 7-alkyl-4-tosyl-2-azabicyclo[2.2.1]hept-5-enes 10, whereas 7-aryl-1-tosyl-3-azatricyclo[2.2.1.0(2.6)]heptan-5-ols 9 (R = aryl) give 2-aryl-5-tosyl-1,2-dihydropyridines 12.

引用

页码：325 / 327

页数：3

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