Pallidal deep brain stimulation in the treatment of Meige syndrome

被引:48
作者
Blomstedt, P. [1 ]
Tisch, S. [2 ]
Hariz, M. I. [1 ,2 ]
机构
[1] Univ Hosp No Sweden, Dept Neurosurg, S-90185 Umea, Sweden
[2] Inst Neurol, London WC1N 3BG, England
来源
ACTA NEUROLOGICA SCANDINAVICA | 2008年 / 118卷 / 03期
关键词
DBS; dystonia; Meige syndrome; pallidal stimulation;
D O I
10.1111/j.1600-0404.2008.00999.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background - Pallidal deep brain stimulation (DBS) of globus pallidus internus (Gpi) has emerged as an effective treatment for dystonia. The experience is however limited concerning focal dystonias and to date only a few cases of pallidal DBS in the treatment of Meige syndrome have been published. Methods/results - We here present a patient with Meige syndrome in whom unilateral pallidal DBS failed to improve the axial symptoms, but bilateral stimulation resulted in a major improvement. The Burke-Fahn-Marsden score (BFM) improved by 71.5% and the patient's blepharospasm was abolished. Conclusions - The results suggest bilateral pallidal DBS may be an effective treatment for Meige syndrome.
引用
收藏
页码:198 / 202
页数:5
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