CELL BIOLOGY Neither brown nor white

被引:36
作者
Cannon, Barbara [1 ]
Nedergaard, Jan [1 ]
机构
[1] Stockholm Univ, Wenner Gren Inst, SE-10691 Stockholm, Sweden
关键词
ADIPOSE-TISSUE; ADULT HUMANS; ADIPOCYTES; FAT; DISTINCT; EXPRESSION; STRESS; MOUSE; MICE;
D O I
10.1038/488286a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Fat cells are usually thought of as being either energy-storing white fat cells or food-burning brown fat cells. The identification of a third type of fat cell in mice and humans might open up new avenues for combating obesity.
引用
收藏
页码:286 / 287
页数:3
相关论文
共 16 条
  • [1] BROWN ADIPOSE TISSUE AND HEAT PRODUCTION IN NEWBORN INFANT
    AHERNE, W
    HULL, D
    [J]. JOURNAL OF PATHOLOGY AND BACTERIOLOGY, 1966, 91 (01): : 223 - &
  • [2] Developmental biology - Neither fat nor flesh
    Cannon, Barbara
    Nedergaard, Jan
    [J]. NATURE, 2008, 454 (7207) : 947 - 948
  • [3] CL316,243 and cold stress induce heterogeneous expression of UCP1 mRNA and protein in rodent brown adipocytes
    Cinti, S
    Cancello, R
    Zingaretti, MC
    Ceresi, E
    De Matteis, R
    Giordano, A
    Himms-Hagen, J
    Ricquier, D
    [J]. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 2002, 50 (01) : 21 - 31
  • [4] Identification and Importance of Brown Adipose Tissue in Adult Humans.
    Cypess, Aaron M.
    Lehman, Sanaz
    Williams, Gethin
    Tal, Ilan
    Rodman, Dean
    Goldfine, Allison B.
    Kuo, Frank C.
    Palmer, Edwin L.
    Tseng, Yu-Hua
    Doria, Alessandro
    Kolodny, Gerald M.
    Kahn, C. Ronald
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (15) : 1509 - 1517
  • [5] UCP1 Ablation Induces Obesity and Abolishes Diet-induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality
    Feldmann, Helena M.
    Golozoubova, Valeria
    Cannon, Barbara
    Nedergaard, Jan
    [J]. CELL METABOLISM, 2009, 9 (02) : 203 - 209
  • [6] Emergence of brown adipocytes in white fat in mice is under genetic control - Effects on body weight and adiposity
    Guerra, C
    Koza, RA
    Yamashita, H
    Walsh, K
    Kozak, LP
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (02) : 412 - 420
  • [7] Lichtenbelt WDV, 2009, NEW ENGL J MED, V360, P1500, DOI 10.1056/NEJMoa0808718
  • [8] Unexpected evidence for active brown adipose tissue in adult humans
    Nedergaard, Jan
    Bengtsson, Tore
    Cannon, Barbara
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2007, 293 (02): : E444 - E452
  • [9] Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes
    Petrovic, Natasa
    Walden, Tomas B.
    Shabalina, Irina G.
    Timmons, James A.
    Cannon, Barbara
    Nedergaard, Jan
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (10) : 7153 - 7164
  • [10] High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans Effects of Cold Exposure and Adiposity
    Saito, Masayuki
    Okamatsu-Ogura, Yuko
    Matsushita, Mami
    Watanabe, Kumiko
    Yoneshiro, Takeshi
    Nio-Kobayashi, Junko
    Iwanaga, Toshihiko
    Miyagawa, Masao
    Kameya, Toshimitsu
    Nakada, Kunihiro
    Kawai, Yuko
    Tsujisaki, Masayuki
    [J]. DIABETES, 2009, 58 (07) : 1526 - 1531