Stem cell transplantation for type 1 diabetes mellitus

被引:0
作者
Voltarelli, Julio C. [1 ]
Barra Couri, Carlos Eduardo [1 ]
机构
[1] Univ Sao Paulo, Ribeirao Preto Sch Med, Dept Clin Med, BR-05508 Sao Paulo, Brazil
来源
DIABETOLOGY & METABOLIC SYNDROME | 2009年 / 1卷
关键词
Systemic Sclerosis; Sitagliptin; Solid Organ Transplant; Bone Marrow Stem Cell; Autologous Hematopoietic Stem Cell Transplantion;
D O I
10.1186/1758-5996-1-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: The use of stem cells to treat type 1 diabetes mellitus has been proposed for many years, both to downregulate the immune system and to provide beta cell regeneration. Conclusion: High dose immunosuppression followed by autologous hematopoietic stem cell transplantation is able to induce complete remission (insulin independence) in most patients with early onset type 1 diabetes mellitus.
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页数:4
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