Biochemistry, Safety, Pharmacological Activities, and Clinical Applications of Turmeric: A Mechanistic Review

被引：82
作者：
Ahmad, Rabia Shabir [1 ]
Hussain, Muhammad Bilal [1 ]
Sultan, Muhammad Tauseef [2 ]
Arshad, Muhammad Sajid [1 ]
Waheed, Marwa [1 ]
Shariati, Mohammad Ali [3 ]
Plygun, Sergey [3 ,4 ,5 ]
Hashempur, Mohammad Hashem [6 ,7 ]
机构：
[1] Govt Coll Univ, Inst Home & Food Sci, Faisalabad 38000, Pakistan
[2] BZU, Multan 66000, Pakistan
[3] Orel State Univ, Lab Biocontrol & Antimicrobial Resistance, Ore 302026, Russia
[4] European Soc Clin Microbiol & Infect Dis, CH-4051 Basel, Switzerland
[5] All Russian Res Inst Phytopathol, Moscow 143050, Russia
[6] Fasa Univ Med Sci, Noncommunicable Dis Res Ctr, Fasa, Iran
[7] Fasa Univ Med Sci, Dept Tradit Persian Med, Fasa, Iran
来源：
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2020年 / 2020卷
关键词：
CURCUMA-LONGA L; CHEMOPREVENTIVE AGENT CURCUMIN; IN-VITRO; DIETARY SUPPLEMENTATION; NATURAL-PRODUCTS; OXIDATIVE DAMAGE; NUCLEAR FACTOR; CANCER; CELLS; PROTECTS;
D O I：
10.1155/2020/7656919
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
Turmeric (Curcuma longa L.) is a popular natural drug, traditionally used for the treatment of a wide range of diseases. Its root, as its most popular part used for medicinal purposes, contains different types of phytochemicals and minerals. This review summarizes what is currently known on biochemistry, safety, pharmacological activities (mechanistically), and clinical applications of turmeric. In short, curcumin is considered as the fundamental constituent in ground turmeric rhizome. Turmeric possesses several biological activities including anti-inflammatory, antioxidant, anticancer, antimutagenic, antimicrobial, antiobesity, hypolipidemic, cardioprotective, and neuroprotective effects. These reported pharmacologic activities make turmeric an important option for further clinical research. Also, there is a discussion on its safety and toxicity.
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页数：14
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