Human gut microbiota and its relationship to health and disease

被引：157

作者：

Wallace, Taylor C. ^{[1
]}

Guarner, Francisco ^{[2
]}

Madsen, Karen ^{[3
]}

Cabana, Michael D. ^{[4
]}

Gibson, Glenn ^{[5
]}

Hentges, Eric ^{[1
]}

Sanders, Mary Ellen ^{[6
]}

机构：

[1] ILSI N Amer, Washington, DC 20005 USA

[2] Univ Hosp Vall dHebron, Digest Syst Res Unit, Barcelona, Spain

[3] Univ Alberta, Div Gastroenterol, Dept Med, Edmonton, AB, Canada

[4] Univ Calif San Francisco, Benioff Childrens Hosp, San Francisco, CA 94143 USA

[5] Univ Reading, Dept Food & Nutr Sci, Reading, Berks, England

[6] Int Sci Assoc Probiot & Prebiot, Davis, CA USA

来源：

NUTRITION REVIEWS | 2011年 / 69卷 / 07期

关键词：

clinical guidelines; gut microbiota; health; intervention; prebiotic; probiotic; INTESTINAL EPITHELIAL-CELLS; LACTOBACILLUS-RHAMNOSUS GG; HUMAN COLONIC MICROBIOTA; HEAT-SHOCK PROTEINS; COLI NISSLE 1917; PROBIOTIC BACTERIA; BIFIDOBACTERIUM STRAINS; DOUBLE-BLIND; BARRIER DYSFUNCTION; DIETARY MODULATION;

D O I：

10.1111/j.1753-4887.2011.00402.x

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Probiotics are live microorganisms that confer a health benefit on the host when administered in appropriate amounts. Over 700 randomized, controlled, human studies have been conducted with probiotics thus far, with the results providing strong support for the use of probiotics in the clinical prevention or treatment of gastrointestinal tract disorders and metabolic syndrome. The present review is based on webinar presentations that were developed by the American Gastroenterological Association (AGA) in partnership with the International Scientific Association for Probiotics and Prebiotics (ISAPP) and the North American branch of the International Life Sciences Institute (ILSI North America). The presentations provided gastroenterologists and researchers with fundamental and current scientific information on the influence of gut microbiota on humanhealth and disease, aswell as clinical intervention strategies and practical guidelines for the use of probiotics and prebiotics. (C) 2011 International Life Sciences Institute

引用

页码：392 / 403

页数：12

共 96 条

[1] Probiotic Escherichia coli Nissle 1917 activates DC and prevents house dust mite allergy through a TLR4-dependent pathway [J].