Necrotizing infundibulo-hypophysitis: an entity too rare to be true?

被引：18

作者：

Gutenberg, Angelika ^{[1
]}

Caturegli, Patrizio ^{[4
]}

Metz, Imke ^{[2
]}

Martinez, Ramon ^{[1
]}

Mohr, Alexander ^{[3
]}

Brueck, Wolfgang ^{[2
]}

Rohde, Veit ^{[1
]}

机构：

[1] Univ Gottingen, Univ Med Ctr, Dept Neurosurg, D-37099 Gottingen, Germany

[2] Univ Gottingen, Univ Med Ctr, Dept Neuropathol, Gottingen, Germany

[3] Univ Gottingen, Univ Med Ctr, Dept Neuroradiol, Gottingen, Germany

[4] Johns Hopkins Univ, Sch Med, Dept Pathol & Immunol, Baltimore, MD USA

来源：

PITUITARY | 2012年 / 15卷 / 02期

关键词：

Hypophysitis; Necrosis; Pituitary infarction; ACUTE PITUITARY NECROSIS; APOPTOTIC CELLS; APOPLEXY; ADENOMAS;

D O I：

10.1007/s11102-011-0307-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a young woman with sudden and severe retroorbital headache, neck pain, and a large sellar mass extending to the suprasellar cistern. A presumptive diagnosis of non-secreting pituitary macroadenoma undergoing apoplexy was made and transphenoidal surgery performed. Histopathology revealed mononuclear infiltration and marked non-hemorrhagic necrosis of the anterior pituitary consistent with a diagnosis of necrotizing infundibulo-hypophysitis. The possible pathogenesis of this rare variant of hypophysitis is discussed.

引用

页码：202 / 208

页数：7

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