Polymorphism in the promoter region of the tumor necrosis factor-alpha gene in cattle herds naturally infected and uninfected with the Bovine Leukemia Virus

被引：11

作者：

Bojarojc-Nosowicz, B. ^{[1
]}

Kaczmarczyk, E. ^{[1
]}

Stachura, A. ^{[1
]}

Kotkiewicz, M. ^{[1
]}

机构：

[1] Univ Warmia & Mazury Olsztyn, Dept Anim Genet, PL-10719 Olsztyn, Poland

来源：

POLISH JOURNAL OF VETERINARY SCIENCES | 2011年 / 14卷 / 04期

关键词：

gene; TNF-alpha; polymorphism; leukosis; lymphocytes; bovine leukemia virus;

D O I：

10.2478/v10181-011-0101-0

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The objective of this study was to describe and compare the genetic structure (TNF-alpha -position 824) of dairy cattle herds infected and not infected with the bovine leukemia virus (BLV). The results of the present study indicate that BLV-positive herds were characterized by similar genetic structure (TNF-alpha -824A/G). The genetic equilibrium in these herds was preserved, but a tendency to increased frequency of GIG homozygotes was found. The genetic structure of the healthy herd differed considerably from that of leukemic herds.

引用

页码：671 / 673

页数：3