Angiotensin II receptor blocker-induced angioedema in the oral floor and epiglottis

被引：12

作者：

Shino, Masato ^{[1
]}

Takahashi, Katsumasa ^{[1
]}

Murata, Takaaki ^{[1
]}

Iida, Hideki ^{[1
]}

Yasuoka, Yoshihito ^{[1
]}

Furuya, Nobuhiko ^{[1
]}

机构：

[1] Gunma Univ, Grad Sch Med, Dept Otolaryngol Head & Neck Surg, Gunma 3718511, Japan

来源：

AMERICAN JOURNAL OF OTOLARYNGOLOGY | 2011年 / 32卷 / 06期

关键词：

CONVERTING ENZYME-INHIBITORS; LOSARTAN; ANTAGONISTS; VALSARTAN;

D O I：

10.1016/j.amjoto.2010.11.014

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

We report the rare case of angioedema (also known as Quincke edema), which was induced by valsartan, an angiotensin II receptor blocker (ARB). ARBs are a new class of antihypertensive agent that is developed to exclude the adverse effects of angiotensin-converting enzyme inhibitors. In theory, ARBs do not contribute to the occurrence of angioedema because they do not increase the serum level of bradykinin, the responsible substance for angioedema. However, some reports of ARB-induced angioedema have recently been published. In this study, we present the forth case and the first Asian case of angioedema due to valsartan, which is one of the ARBs. Otolaryngologist should be wary of the prescribing ARB and discontinue ARBs treatment soon, if angioedema is recognized. (C) 2011 Elsevier Inc. All rights reserved.

引用

页码：624 / 626

页数：3

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