Therapeutic drug monitoring (TDM) of gentamicin in critically ill neonates

被引：0

作者：

Martinkova, J. ^{[1
]}

Pokorna, P. ^{[1
]}

Zahora, J. ^{[1
]}

Selke-Krulichova, I. ^{[1
]}

机构：

[1] Charles Univ Prague, Fac Med, Dept Pharmacol, Hradec Kralove, Czech Republic

来源：

PROCEEDINGS OF THE 8TH CONGRESS OF THE EUROPEAN ASSOCIATION FOR CLINICAL PHARMACOLOGY AND THERAPEUTICS | 2007年

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

First dose plasma concentrations (Cpl) of GE in neonates during the first week of life seem to be predictive of steady state Cpl in those without co-variates significantly modifying pharmacokinetics (PK) of GE such as water retention (systemic capillary leak syndrome) and furosemide given as a bolus dose > 1mg/kg BW or continuous i. v. infusion.

引用

页码：163 / +

页数：2

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