ACCURACY OF WHOLE-BODY PET AND PET-CT IN INITIAL M STAGING OF HEAD AND NECK CANCER: A META-ANALYSIS

被引：24

作者：

Xu, Guo-Zeng ^{[1
]}

Zhu, Xiao-Dong ^{[1
]}

Li, Ming-Yao ^{[1
]}

机构：

[1] Guangxi Med Univ, Canc Hosp, Dept Radiat Oncol, Nanning, Peoples R China

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2011年 / 33卷 / 01期

关键词：

head and neck cancer; PET; PET-CT; staging; meta-analysis; POSITRON-EMISSION-TOMOGRAPHY; SQUAMOUS-CELL CARCINOMA; PREVIOUSLY UNTREATED HEAD; DISTANT METASTASES; NASOPHARYNGEAL CARCINOMA; FDG-PET; COMPUTED-TOMOGRAPHY; F-18-FDG PET; DIAGNOSTIC-ACCURACY; PRIMARY TUMORS;

D O I：

10.1002/hed.21400

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Background. A meta-analysis was conducted to evaluate the accuracy of whole-body positron emission tomography (PET) and PET-CT in initial M staging of head and neck cancer. Methods. After a systematic review of English language studies, sensitivity, specificity, and other measures of whole-body PET and PET-CT were pooled. Summary receiver operating characteristic (SROC) curves were also used to summarize overall test performance. Results. Eight PET and 7 PET-CT studies were identified. The pooled sensitivity estimates for PET and PET-CT were 0.848 (95% confidence interval [CI], 0.776-0.905) and 0.875 (95% CI, 0.787-0.936). The pooled specificity estimates were 0.952 (95% CI, 0.933-0.967) and 0.950 (95% CI, 0.931-0.964). The Q* index estimates for PET-CT (0.9409) were not significantly higher than for PET (0.9154; p > .05). Conclusion. Whole-body PET and PET-CT have good diagnostic performance in initial M staging of head and neck cancer; although PET-CT tends to have higher accuracy than PET. (C) 2010 Wiley Periodicals, Inc. Head Neck 33: 87-94, 2011

引用

页码：87 / 94

页数：8

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