Copper(II)-Promoted C-C Bond Formation by Oxidative Coupling of Two C(sp3)-H Bonds Adjacent to Carbonyl Group to Construct 1,4-Diketones and Tetrasubstituted Furans

被引：25

作者：

Mao, Shuai ^{[1
]}

Gao, Ya-Ru ^{[1
]}

Zhang, Shao-Liang ^{[1
]}

Guo, Dong-Dong ^{[1
]}

Wang, Yong-Qiang ^{[1
]}

机构：

[1] NW Univ Xian, Key Lab Synthet & Nat Funct Mol Chem, Minist Educ, Dept Chem & Mat Sci, Xian 710069, Peoples R China

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 2015卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Synthetic methods; C-C coupling; Oxidation; Copper; Oxygen heterocycles; CATALYZED SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; REGIOSELECTIVE SYNTHESIS; AROMATIC POLYAMIDES; H FUNCTIONALIZATION; TERTIARY-AMINES; BENZYL KETONES; STRATEGY; CYCLIZATION; ALKYNES;

D O I：

10.1002/ejoc.201403274

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The copper(II)-promoted C-C bond formation from the coupling of two C(sp(3))-H bonds that are adjacent to a carbonyl group was achieved. This protocol offers a simple and efficient approach to 2,3-disubstituted 1,4-diketones and tetrasubstituted furans. This method features a wide substrate scope and high functional group tolerance.

引用

收藏

页码：876 / 885

页数：10

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