The microbiota-gut-brain axis: learning from intestinal bacteria?

被引:76
作者
Bercik, Premysl [1 ]
机构
[1] McMaster Univ, Fac Hlth Sci, Farncombe Family Digest Hlth Inst, Hamilton, ON L8N 3Z5, Canada
关键词
ANXIETY-LIKE BEHAVIOR; MICE; INFECTION; SYSTEM; INFLAMMATION; INDUCTION;
D O I
10.1136/gut.2010.226779
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:288 / 289
页数:4
相关论文
共 16 条
[1]   Host-bacterial mutualism in the human intestine [J].
Bäckhed, F ;
Ley, RE ;
Sonnenburg, JL ;
Peterson, DA ;
Gordon, JI .
SCIENCE, 2005, 307 (5717) :1915-1920
[2]   Review article: the current pharmacological therapies for hepatic encephalopathy [J].
Bass, N. M. .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2007, 25 :23-31
[3]   Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice [J].
Bercik, Premysl ;
Verdu, Elena F. ;
Foster, Jane A. ;
Macri, Joseph ;
Potter, Murray ;
Huang, Xiaxing ;
Malinowski, Paul ;
Jackson, Wendy ;
Blennerhassett, Patricia ;
Neufeld, Karen A. ;
Lu, Jun ;
Khan, Waliul I. ;
Corthesy-Theulaz, Irene ;
Cherbut, Christine ;
Bergonzelli, Gabriela E. ;
Collins, Stephen M. .
GASTROENTEROLOGY, 2010, 139 (06) :2102-U409
[4]   Role of gut-brain axis in persistent abnormal feeding behavior in mice following eradication of Helicobacter pylori infection [J].
Bercik, Premysl ;
Verdu, Elena F. ;
Foster, Jane A. ;
Lu, Jun ;
Scharringa, Angela ;
Kean, Iain ;
Wang, Lu ;
Blennerhassett, Patricia ;
Collins, Stephen M. .
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2009, 296 (03) :R587-R594
[5]   From inflammation to sickness and depression: when the immune system subjugates the brain [J].
Dantzer, Robert ;
O'Connor, Jason C. ;
Freund, Gregory G. ;
Johnson, Rodney W. ;
Kelley, Keith W. .
NATURE REVIEWS NEUROSCIENCE, 2008, 9 (01) :46-57
[6]   Diversity of the human intestinal microbial flora [J].
Eckburg, PB ;
Bik, EM ;
Bernstein, CN ;
Purdom, E ;
Dethlefsen, L ;
Sargent, M ;
Gill, SR ;
Nelson, KE ;
Relman, DA .
SCIENCE, 2005, 308 (5728) :1635-1638
[7]   Bacterial infection causes stress-induced memory dysfunction in mice [J].
Gareau, Melanie G. ;
Wine, Eytan ;
Rodrigues, David M. ;
Cho, Joon Ho ;
Whary, Mark T. ;
Philpott, Dana J. ;
MacQueen, Glenda ;
Sherman, Philip M. .
GUT, 2011, 60 (03) :307-317
[8]   Activation in vagal afferents and central autonomic pathways:: Early responses to intestinal infection with Campylobacter jejuni [J].
Goehler, LE ;
Gaykema, RPA ;
Opitz, N ;
Reddaway, R ;
Badr, N ;
Lyte, M .
BRAIN BEHAVIOR AND IMMUNITY, 2005, 19 (04) :334-344
[9]   Immune adaptations that maintain homeostasis with the intestinal microbiota [J].
Hooper, Lora V. ;
Macpherson, Andrew J. .
NATURE REVIEWS IMMUNOLOGY, 2010, 10 (03) :159-169
[10]   Molecular analysis of commensal host-microbial relations hips in the intestine [J].
Hooper, LV ;
Wong, MH ;
Thelin, A ;
Hansson, L ;
Falk, PC ;
Gordon, JI .
SCIENCE, 2001, 291 (5505) :881-884