Superparamagnetic iron oxide nanoparticles functionalized with peptides by electrostatic interactions

被引:21
|
作者
Hildebrandt, Nicole
Hermsdorf, Dana
Signorell, Ruth
Schmitz, Stephan A.
Diederichsen, Ulf [1 ]
机构
[1] Univ Gottingen, Inst Organ & Biomol Chem, Tammannstr 2, D-37077 Gottingen, Germany
[2] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada
[3] Hammersmith Hosp, Imperial Coll, Fac Med, London W12 0HS, England
关键词
electron microscopy; molecular recognition; nanoparticles; peptides; self-assembly;
D O I
10.3998/ark.5550190.0008.508
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Superparamagnetic iron oxide nanoparticles coated with dextran were functionalized with negatively charged functionalities in order to connect specific peptide labels by electrostatic interactions. Peptide binding on the nanoparticles was indicated by HR-TEM, an electrospray scanning mobility particle sizer, and fluorescence measurements.
引用
收藏
页码:79 / 90
页数:12
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