White blood cell count and cardiovascular biomarkers of atherosclerosis

被引：19

作者：

Sekitani, Yui ^{[1
]}

Hayashida, Naomi ^{[1
]}

Kadota, Koichiro ^{[2
]}

Yamasaki, Hironori ^{[3
]}

Abiru, Norio ^{[4
]}

Nakazato, Mio ^{[5
]}

Maeda, Takahiro ^{[5
]}

Ozono, Yoshiyuki ^{[2
]}

Takamura, Noboru ^{[1
]}

机构：

[1] Nagasaki Univ, Grad Sch Biomed Sci, Dept Radiat Epidemiol, Nagasaki 8528523, Japan

[2] Nagasaki Univ, Grad Sch Biomed Sci, Dept Gen Med, Nagasaki 8528523, Japan

[3] Nagasaki Univ, Ctr Hlth & Community Med, Nagasaki 8528523, Japan

[4] Nagasaki Univ, Grad Sch Biomed Sci, Unit Translat Med, Dept Endocrinol & Metab, Nagasaki 8528523, Japan

[5] Nagasaki Univ, Grad Sch Biomed Sci, Dept Isl & Community Med, Nagasaki 8528523, Japan

来源：

BIOMARKERS | 2010年 / 15卷 / 05期

基金：

日本学术振兴会;

关键词：

Cardio-ankle vascular index; carotid intima-media thickness; metabolic syndrome; INTIMA-MEDIA THICKNESS; CORONARY-HEART-DISEASE; PULSE-WAVE VELOCITY; VASCULAR INDEX CAVI; TYPE-2; DIABETES-MELLITUS; LEUKOCYTE COUNT; CAROTID ATHEROSCLEROSIS; ARTERIAL STIFFNESS; LIPOPROTEIN CHOLESTEROL; RISK;

D O I：

10.3109/1354750X.2010.486870

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Objective: To investigate the association with white blood cells (WBC) and atherosclerotic parameters including cardio-ankle vascular index (CAVI) and carotid intima-media thickness (CIMT) in the general population. Methods: We investigated the relationship between WBC count and metabolic syndrome components, CAVI and CIMT in 3738 Japanese study participants. Results: WBC count weakly correlated with CAVI in men (beta = 0.61, p = 0.043), but not in women (beta = 0.35, p = 0.17). On the other hand, WBC did not correlate with CIMT in either men or women (p = 0.41 and p = 0.71, respectively). Conclusion: WBC count was associated with lipids, blood pressure and body mass index, although the correlations with CAVI and CIMT were weak or absent.

引用

页码：454 / 460

页数：7

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