Artificial Cytoskeletal Structures Within Enzymatically Active Bio-inorganic Protocells

被引：43

作者：

Kumar, Ravinash Krishna ^{[1
]}

Li, Mei ^{[1
]}

Olof, Sam N. ^{[1
,2
]}

Patil, Avinash J. ^{[1
]}

Mann, Stephen ^{[1
]}

机构：

[1] Univ Bristol, Sch Chem, Ctr Organized Matter Chem, Bristol BS8 1TS, Avon, England

[2] Univ Bristol, Ctr NSQI, Bristol Ctr Funct Nanomat, Bristol BS8 1FD, Avon, England

来源：

SMALL | 2013年 / 9卷 / 03期

基金：

英国工程与自然科学研究理事会;

关键词：

protocells; artificial cytoskeletons; colloidosomes; artificial cells; BIOCHEMICAL REACTIONS; ENZYME CATALYSIS; MODEL PROTOCELL; MINIMAL CELLS; VESICLES; COMPARTMENTS; POLYMER; MEDIA; LIFE;

D O I：

10.1002/smll.201201539

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The fabrication of enzymatically active, semi-permeable bio-inorganic protocells capable of self-assembling a cytoskeletal-like interior and undergoing small-molecule dephosphorylation reactions is described. Reversible disassembly of an amino acid-derived supramolecular hydrogel within the internalized reaction space is used to tune the enzymatic activity of the nanoparticle-bounded inorganic compartments. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：357 / 362

页数：6

共 5 条

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