Electron Diffraction of 3D Molecular Crystals

被引：56
作者：
Saha, Ambarneil [1 ,2 ]
Nia, Shervin S. [1 ,2 ]
Rodriguez, Jose A. [1 ,2 ]
机构：
[1] Univ Calif Los Angeles, UCLA DOE Inst Genom & Prote, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
来源：
CHEMICAL REVIEWS | 2022年 / 122卷 / 17期
关键词：
ACTIVE PHARMACEUTICAL INGREDIENTS; INITIO STRUCTURE DETERMINATION; STRUCTURE-BASED INHIBITORS; X-RAY CRYSTALLOGRAPHY; RADIATION-DAMAGE; PHASE DETERMINATION; SCATTERING FACTORS; DYNAMICAL DIFFRACTION; PRECESSION TECHNIQUE; HYDROGEN POSITIONS;
D O I：
10.1021/acs.chemrev.1c00879
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Electron crystallography has a storied history which rivals that of its more established X-ray-enabled counterpart. Recent advances in data collection and analysis have sparked a renaissance in the field, opening a new chapter for this venerable technique. Burgeoning interest in electron crystallography has spawned innovative methods described by various interchangeable labels (3D ED, MicroED, cRED, etc.). This Review covers concepts and findings relevant to the practicing crystallographer, with an emphasis on experiments aimed at using electron diffraction to elucidate the atomic structure of three-dimensional molecular crystals.
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收藏
页码：13883 / 13914
页数：32
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