1-Substituted 5-Aminotetrazoles: Syntheses from CNN3 with Primary Amines

被引：82
作者：
Joo, Young-Hyuk [1 ]
Shreeve, Jean'ne M. [1 ]
机构：
[1] Univ Idaho, Dept Chem, Moscow, ID 83844 USA
来源：
ORGANIC LETTERS | 2008年 / 10卷 / 20期
关键词：
D O I：
10.1021/ol8019742
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
1-Substituted 5-aminotetrazoles were prepared in situ by an excellent reaction of cyanogen azide and primary amines to generate an imidoyl azide as an intermediate in acetonitrile/water. After cyclization, the intermediate gave 1-substituted aminotetrazole in good yield. This protocol also was utilized in the syntheses of bis- and tris(1-substituted 5-aminotetrazole) derivatives.
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页码：4665 / 4667
页数：3
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