Tracing Bioavailability of ZnO Nanoparticles Using Stable Isotope Labeling

被引:58
作者
Larner, Fiona [1 ]
Dogra, Yuktee [2 ]
Dybowska, Agnieszka [3 ]
Fabrega, Julia [2 ]
Stolpe, Bjoern [4 ]
Bridgestock, Luke J. [1 ]
Goodhead, Rhys [5 ]
Weiss, Dominik J. [1 ,3 ]
Moger, Julian [5 ]
Lead, Jamie R. [4 ]
Valsami-Jones, Eugenia [3 ]
Tyler, Charles R. [2 ]
Galloway, Tamara S. [2 ]
Rehkaemper, Mark [1 ,3 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Earth Sci & Engn, London SW7 2AZ, England
[2] Univ Exeter, Coll Life & Environm Sci, Exeter EX4 4QL, Devon, England
[3] Nat Hist Museum, Dept Mineral, London SW7 5BD, England
[4] Univ Birmingham, Sch Geog Earth & Environm Sci, Birmingham B15 2TT, W Midlands, England
[5] Univ Exeter, Sch Phys, Exeter EX4 4QL, Devon, England
基金
英国工程与自然科学研究理事会;
关键词
COROPHIUM-VOLUTATOR CRUSTACEA; METAL-OXIDE NANOPARTICLES; CHRONIC TOXICITY; ZINC; SEDIMENT; ACCUMULATION; EXPOSURE; COPPER; AGGLOMERATION; CONTAMINANTS;
D O I
10.1021/es302602j
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Zinc oxide nanoparticles (ZnO NPs) are widely used in commercial products and knowledge of their environmental fate is a priority for ecological protection. Here we synthesized model ZnO NPs that were made from and thus labeled with the stable isotope Zn-68 and this enables highly sensitive and selective detection of labeled components against high natural Zn background levels. We combine high precision stable isotope measurements and novel bioimaging techniques to characterize parallel water borne exposures of the common mudshrimp Corophium volutator to (ZnO)-Zn-68 NPs, bulk (ZnO)-Zn-68, and soluble (ZnCl2)-Zn-68 in the presence of sediment. C. volutator is an important component of coastal ecosystems where river-borne NPs will accumulate and is used on a routine basis for toxicity assessments Our results demonstrate that ionic Zn from ZnO NPs is bioavailable to C volutator and that Zn uptake is active. Bioavailability appears to be governed primarily by the dissolved Zn content of the water, whereby Zn uptake occurs via the aqueous phase and/or the ingestion of sediment particles with adsorbed Zn from dissolution of ZnO particles. The high sorption capacity of sediments for Zn thus enhances the potential for trophic transfer of Zn derived from readily soluble ZnO NPs. The uncertainties of our isotopic data are too large, however, to conclusively rule out any additional direct uptake route of ZnO NPs by C. volutator.
引用
收藏
页码:12137 / 12145
页数:9
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