Label-free biosensing using cascaded double-microring resonators integrated with microfluidic channels

被引：38
作者：
Chen, Yangqing [1 ]
Yu, Fang [1 ]
Yang, Chang [1 ]
Song, Jinyan [1 ]
Tang, Longhua [1 ]
Li, Mingyu [1 ]
He, Jian-Jun [1 ]
机构：
[1] Zhejiang Univ, Dept Opt Engn, State Key Lab Modern Opt Instrumentat, Hangzhou 310027, Zhejiang, Peoples R China
来源：
OPTICS COMMUNICATIONS | 2015年 / 344卷
基金：
国家高技术研究发展计划(863计划); 中国国家自然科学基金;
关键词：
Cascaded double-microring resonators; Biosensor; Label-free; RING RESONATORS; SILICON; SENSORS; SURFACE; ARRAY;
D O I：
10.1016/j.optcom.2015.01.028
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
Fast and accurate quantitative measurement of biologically relevant molecules has been demonstrated for medical diagnostics and drug applications in photonic integrated circuits. Herein, we reported a highly-sensitive optical biosensor based on cascaded double-microring resonators. The sensor was integrated with microfluidic channels and investigated with its label-free detection capability. With a wavelength resolution of 0.47 nm, the measured binding capacity of the antibody on the surface exhibits reliable detection limit down to 7.10 mu g/mL using human immunoglobulin G (hIgG). (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码：129 / 133
页数：5
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