Label-free biosensing using cascaded double-microring resonators integrated with microfluidic channels

被引：38

作者：

Chen, Yangqing ^{[1
]}

Yu, Fang ^{[1
]}

Yang, Chang ^{[1
]}

Song, Jinyan ^{[1
]}

Tang, Longhua ^{[1
]}

Li, Mingyu ^{[1
]}

He, Jian-Jun ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Opt Engn, State Key Lab Modern Opt Instrumentat, Hangzhou 310027, Zhejiang, Peoples R China

来源：

OPTICS COMMUNICATIONS | 2015年 / 344卷

基金：

中国国家自然科学基金; 国家高技术研究发展计划(863计划);

关键词：

Cascaded double-microring resonators; Biosensor; Label-free; RING RESONATORS; SILICON; SENSORS; SURFACE; ARRAY;

D O I：

10.1016/j.optcom.2015.01.028

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Fast and accurate quantitative measurement of biologically relevant molecules has been demonstrated for medical diagnostics and drug applications in photonic integrated circuits. Herein, we reported a highly-sensitive optical biosensor based on cascaded double-microring resonators. The sensor was integrated with microfluidic channels and investigated with its label-free detection capability. With a wavelength resolution of 0.47 nm, the measured binding capacity of the antibody on the surface exhibits reliable detection limit down to 7.10 mu g/mL using human immunoglobulin G (hIgG). (C) 2015 Elsevier B.V. All rights reserved.

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收藏

页码：129 / 133

页数：5

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