Phylogeography of the Y-chromosome haplogroup C in northern Eurasia

被引：48
作者：
Malyarchuk, Boris [1 ]
Derenko, Miroslava
Denisova, Galina
Wozniak, Marcin [2 ]
Grzybowski, Tomasz [2 ]
Dambueva, Irina [3 ]
Zakharov, Ilia [4 ]
机构：
[1] Russian Acad Sci, Inst Biol Problems N, Genet Lab, Magadan 685000, Russia
[2] Nicolaus Copernicus Univ Torun, Ludwik Rydygier Med Coll, Inst Forens Med, PL-85094 Bydgoszcz, Poland
[3] Russian Acad Sci, Inst Gen & Expt Biol, Ulan Ude 670047, Russia
[4] Russian Acad Sci, NI Vavilov Gen Genet Res Inst, Moscow 119991, Russia
来源：
ANNALS OF HUMAN GENETICS | 2010年 / 74卷
基金：
俄罗斯基础研究基金会;
关键词：
Y-chromosome; haplogroup; STR; South Siberia; Eastern Europe; phylogeography; SIBERIAN POPULATIONS; MITOCHONDRIAL-DNA; DIVERGENCE TIME; HUNTER-GATHERER; SOUTH SIBERIA; EAST-ASIA; HAPLOTYPES; RESOLUTION; DIVERSITY; ORIGINS;
D O I：
10.1111/j.1469-1809.2010.00601.x
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
P>To reconstruct the phylogenetic structure of Y-chromosome haplogroup (hg) C in populations of northern Eurasia, we have analyzed the diversity of microsatellite (STR) loci in a total sample of 413 males from 18 ethnic groups of Siberia, Eastern Asia and Eastern Europe. Analysis of SNP markers revealed that all Y-chromosomes studied belong to hg C3 and its subhaplogroups C3c and C3d, although some populations (such as Mongols and Koryaks) demonstrate a relatively high input (more than 30%) of yet unidentified C3* haplotypes. Median joining network analysis of STR haplotypes demonstrates that Y-chromosome gene pools of populations studied are characterized by the presence of DNA clusters originating from a limited number of frequent founder haplotypes. These are subhaplogroup C3d characteristic for Mongolic-speaking populations, "star cluster" in C3* paragroup, and a set of DYS19 duplicated C3c Y-chromosomes. All these DNA clusters show relatively recent coalescent times (less than 3000 years), so it is probable that founder effects, including social selection resulting in high male fertility associated with a limited number of paternal lineages, may explain the observed distribution of hg C3 lineages.
引用
收藏
页码：539 / 546
页数：8
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