Gut Microbiota in Psoriasis

被引：61

作者：

Buhas, Mihaela Cristina ^{[1
]}

Gavrilas, Laura Ioana ^{[2
]}

Candrea, Rares ^{[3
]}

Catinean, Adrian ^{[4
]}

Mocan, Andrei ^{[5
]}

Miere, Doina ^{[2
]}

Tataru, Alexandru ^{[1
]}

机构：

[1] Iuliu Hatieganu Univ Med & Pharm, Dept Dermatol, Cluj Napoca 400423, Romania

[2] Iuliu Hatieganu Univ Med & Pharm, Dept Bromatol Hyg Nutr, 23 Marinescu St, Cluj Napoca 400337, Romania

[3] Iuliu Hatieganu Univ Med & Pharm, Bachelor Program Nutr & Dietet, Cluj Napoca 400337, Romania

[4] Iuliu Hatieganu Univ Med & Pharm, Fac Med, Dept Internal Med Gastroenterol, Cluj Napoca 400337, Romania

[5] Iuliu Hatieganu Univ Med & Pharm, Dept Pharmaceut Bot, 23 Marinescu St, Cluj Napoca 400337, Romania

来源：

NUTRIENTS | 2022年 / 14卷 / 14期

关键词：

psoriasis; microbiota; dietary approaches; probiotics; prebiotics; RESVERATROL REDUCES OBESITY; INFLAMMATORY-BOWEL-DISEASE; SKIN INFLAMMATION; CELIAC-DISEASE; OPEN-LABEL; QUERCETIN; RISK; IMPROVES; MICE; TOLERABILITY;

D O I：

10.3390/nu14142970

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Psoriasis is a chronic inflammatory skin disease with autoimmune pathogenic characteristics and is caused by chronic inflammation, which results in uncontrolled keratinocyte growth and defective differentiation. The link between the gut microbiota and immune system regulation opened a novel angle to understand the pathogenesis of many chronic multifactorial diseases, including psoriasis. Current evidence suggests that modulation of the gut microbiota, both through dietary approaches and through supplementation with probiotics and prebiotics, could represent a novel therapeutic approach. The present work aims to highlight the latest scientific evidence regarding the microbiome alterations of psoriatic patients, as well as state of the art insights in terms of microbiome-targeted therapies as promising preventive and therapeutic tools for psoriasis.

引用

页数：21

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