Presence of periodontopathic bacteria in coronary arteries from patients with chronic periodontitis

被引：41

作者：

Marcelino, Silvia L. ^{[2
]}

Gaetti-Jardim, Elerson, Jr. ^{[1
]}

Nakano, Viviane ^{[1
]}

Canonico, Luis A. D. ^{[2
]}

Nunes, Fabio D. ^{[3
]}

Lotufo, Roberto F. M. ^{[2
]}

Pustiglioni, Francisco E. ^{[2
]}

Romito, Giuseppe A. ^{[2
]}

Avila-Campos, Mario J. ^{[1
]}

机构：

[1] Univ Sao Paulo, Inst Biomed Sci, Dept Microbiol, Anaerobe Lab, Sao Paulo, Brazil

[2] Univ Sao Paulo, Sch Dent, Dept Stomatol, Div Periodont, Sao Paulo, Brazil

[3] Univ Sao Paulo, Sch Dent, Dept Oral Pathol, Sao Paulo, Brazil

来源：

ANAEROBE | 2010年 / 16卷 / 06期

基金：

巴西圣保罗研究基金会;

关键词：

Atherosclerosis; Coronary arteries; Chronic periodontitis; Periodontal bacteria; POLYMERASE CHAIN-REACTION; ATHEROMATOUS PLAQUES; PATHOGENS; IDENTIFICATION; VESSELS; DISEASE; LESIONS; DNA;

D O I：

10.1016/j.anaerobe.2010.08.007

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In this study the presence of periodontopathic pathogens in atheromatous plaques removed from coronary arteries of patients with chronic periodontitis and periodontally healthy subjects by PCR was detected. Our results indicate a significant association between the presence of Porphyromonas gingivalis and atheromas, and the periodontal bacteria in oral biofilm may find a way to reach arteries. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：629 / 632

页数：4

共 19 条

[1] Microbiologic analysis of periodontal pockets and carotid atheromatous plaques in advanced chronic periodontitis patients [J].

Aimetti, Mario ;

Romano, Federica ;

Nessi, Franco .

JOURNAL OF PERIODONTOLOGY, 2007, 78 (09) :1718-1723

[2] Distribution of Porphyromonas gingivalis strains with fimA genotypes in periodontitis patients [J].

Amano, A ;

Nakagawa, I ;

Kataoka, K ;

Morisaki, I ;

Hamada, S .

JOURNAL OF CLINICAL MICROBIOLOGY, 1999, 37 (05) :1426-1430

[3] Polymerase chain reaction detection of 8 putative periodontal pathogens in subgingival plaque of gingivitis and advanced periodontitis lesions [J].

Ashimoto, A ;

Chen, C ;

Bakker, I ;

Slots, J .

ORAL MICROBIOLOGY AND IMMUNOLOGY, 1996, 11 (04) :266-273

[4] Arbitrarily primed-polymerase chain reaction for identification and epidemiologic subtyping of oral isolates of Fusobacterium nucleatum [J].

Avila-Campos, MJ ;

Sacchi, CT ;

Whitney, AM ;

Steigerwalt, AG ;

Mayer, LW .

JOURNAL OF PERIODONTOLOGY, 1999, 70 (10) :1202-1208

[5] GenBank [J].

Benson, DA ;

Karsch-Mizrachi, I ;

Lipman, DJ ;

Ostell, J ;

Rapp, BA ;

Wheeler, DL .

NUCLEIC ACIDS RESEARCH, 2002, 30 (01) :17-20

[6] Risk factors for cardiovascular disease in patients with periodontitis [J].

Buhlin, K ;

Gustafsson, A ;

Pockley, AG ;

Frostegård, J ;

Klinge, B .

EUROPEAN HEART JOURNAL, 2003, 24 (23) :2099-2107

[7] Prevalence of periodontal pathogens in subgingival lesions, atherosclerotic plaques and healthy blood vessels: a preliminary study [J].

Elkaim, R. ;

Dahan, M. ;

Kocgozlu, L. ;

Werner, S. ;

Kanter, D. ;

Kretz, J. G. ;

Tenenbaum, H. .

JOURNAL OF PERIODONTAL RESEARCH, 2008, 43 (02) :224-231

[8] Identification of periodontal pathogens in atherosclerotic vessels [J].

Fiehn, NE ;

Larsen, T ;

Christiansen, N ;

Holmstrup, P ;

Schroeder, TV .

JOURNAL OF PERIODONTOLOGY, 2005, 76 (05) :731-736

[9] Quantitative detection of periodontopathic bacteria in atherosclerotic plaques from coronary arteries [J].

Gaetti-Jardim, Elerson, Jr. ;

Marcelino, Silvia L. ;

Feitosa, Alfredo C. R. ;

Romito, Giuseppe A. ;

Avila-Campos, Mario J. .

JOURNAL OF MEDICAL MICROBIOLOGY, 2009, 58 (12) :1568-1575

[10]

Haffajee A D, 1994, Periodontol 2000, V5, P78, DOI 10.1111/j.1600-0757.1994.tb00020.x

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