Flexible Gold-Catalyzed Regioselective Oxidative Difunctionalization of Unactivated Alkenes

被引：188
|
作者：
de Haro, Teresa [1 ]
Nevado, Cristina [1 ]
机构：
[1] Univ Zurich, Inst Organ Chem, CH-8006 Zurich, Switzerland
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 04期
关键词：
alkenes; amino alcohols; gold; homogeneous catalysis; oxidation; N-FLUOROBENZENESULFONIMIDE; REDUCTIVE ELIMINATION; BOND FORMATION; C-O; DIAMINATION; AMINOACETOXYLATION; AMINOHYDROXYLATION; NITRILES; AMINOOXYGENATION; DERIVATIVES;
D O I：
10.1002/anie.201005763
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
AuI/AuIII catalytic cycles can trigger three highly regioselective alkene difunctionalization processes that involve the formation of C(sp3)iO, C(sp3)iN, and C(sp3)iC(sp 2) bonds. The reaction can proceed by reductive elimination on the oxidized gold center with complete retention of the configuration or through two subsequent nucleophilic substitution reactions via an aziridine intermediate. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：906 / 910
页数：5
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