Suppression of estrogen-withdrawal headache with extended transdermal contraception

被引：32

作者：

LaGuardia, KD ^{[1
]}

Fisher, AC ^{[1
]}

Bainbridge, JD ^{[1
]}

LoCoco, JM ^{[1
]}

Friedman, AJ ^{[1
]}

机构：

[1] Ortho McNeil Pharmaceut Inc, Clin Affairs, Raritan, NJ 08869 USA

来源：

FERTILITY AND STERILITY | 2005年 / 83卷 / 06期

关键词：

D O I：

10.1016/j.fertnstert.2004.12.048

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

A randomized clinical trial was conducted with 239 women at nine clinical research sites to compare bleeding profile, headache frequency, and subject satisfaction with the transdermal contraceptive, ORTHO EVRA((R)) (norelgestromin/ethinyl estradiol transdermal system) used in an extended regimen (84 days) with a traditional, 28-day cyclic regimen. In a majority of women studied, compared with cyclic use, extended use of transdermal norelgestromin/ethinyl estradiol delayed menses and reduced the total incidence of mean headache days during the hormone-free interval. (c) 2005 by American Society for Reproductive Medicine.

引用

页码：1875 / 1877

页数：3

共 5 条

[1] PREVENTION OF MENSTRUAL MIGRAINE BY PERCUTANEOUS ESTRADIOL [J].

DELIGNIERES, B ;

VINCENS, M ;

MAUVAISJARVIS, P ;

MAS, JL ;

TOUBOUL, PJ ;

BOUSSER, MG .

BMJ-BRITISH MEDICAL JOURNAL, 1986, 293 (6561) :1540-1540

[2] HEADACHE AND SEX-HORMONE THERAPY [J].

DENNERSTEIN, L ;

LABY, B ;

BURROWS, GD ;

HYMAN, GJ .

HEADACHE, 1978, 18 (03) :146-153

[3] MIGRAINE AND REPRODUCTIVE HORMONES THROUGHOUT MENSTRUAL-CYCLE [J].

EPSTEIN, MT ;

HOCKADAY, JM ;

HOCKADAY, TDR .

LANCET, 1975, 1 (7906) :543-547

[4] ESTROGEN-WITHDRAWAL MIGRAINE .1. DURATION OF EXPOSURE REQUIRED AND ATTEMPTED PROPHYLAXIS BY PREMENSTRUAL ESTROGEN ADMINISTRATION [J].

SOMERVILLE, BW .

NEUROLOGY, 1975, 25 (03) :239-244

[5] Hormone withdrawal symptoms in oral contraceptive users [J].

Sulak, PJ ;

Scow, RD ;

Preece, C ;

Riggs, MW ;

Kuehl, TJ .

OBSTETRICS AND GYNECOLOGY, 2000, 95 (02) :261-266

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