Vinyltetrazoles: I. Synthesis of NH-Unsubstituted 5-Vinyltetrazole

被引：7

作者：

Ostrovskii, V. A. ^{[1
]}

Aleshunin, P. A. ^{[1
]}

Zubarev, V. Yu. ^{[1
]}

Popova, E. A. ^{[1
]}

Pavlyukova, Yu. N. ^{[1
]}

Shumilova, E. A. ^{[1
]}

Trifonov, R. E. ^{[1
]}

Artamonova, T. V. ^{[1
]}

机构：

[1] Tech Univ, St Petersburg State Technol Inst, St Petersburg 190013, Russia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 46卷 / 11期

基金：

俄罗斯基础研究基金会;

关键词：

NITRILES;

D O I：

10.1134/S1070428010110126

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The NH-unsubstituted 5-vinyltetrazole was obtained in 55% yield by exhaustive methylation of 5-(beta-dimethylaminoethyl)tetrazole with dimethyl sulfate at the terminal dimethylamino group with the subsequent elimination of a proton from the alpha-CH2 group and Hofmann beta-cleavage of the intermediate 5-(beta-trimethylammoniumethyl)tetrazolide methyl sulfate. The microwave irradiation was shown to reduce 5-fold the time of the synthesis of the initial substrate, 5-(beta-dimethylaminoethyl)tetrazole.

引用

页码：1678 / 1681

页数：4

共 17 条

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