Management of perianal fistulas in Crohn's disease: An up-to-date review

被引:66
作者
Marzo, Manuela [1 ]
Felice, Carla [1 ]
Pugliese, Daniela [1 ]
Andrisani, Gianluca [1 ]
Mocci, Giammarco [1 ]
Armuzzi, Alessandro [1 ]
Guidi, Luisa [1 ]
机构
[1] Univ Cattolica Sacro Cuore, IBD Unit, Complesso Integrato Columbus, I-00168 Rome, Italy
关键词
Crohn's disease; Perianal fistula; Surgery; Drug therapy; Tumor necrosis factor alpha; INFLAMMATORY-BOWEL-DISEASE; INFLIXIMAB MAINTENANCE THERAPY; RANDOMIZED CLINICAL-TRIAL; COMBINED SETON PLACEMENT; COMPLEX ANAL FISTULA; FIBRIN GLUE; ANORECTAL FISTULAS; HYDROGEN-PEROXIDE; LOCAL INJECTION; IN-ANO;
D O I
10.3748/wjg.v21.i5.1394
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Perianal disease is one of the most disabling manifestations of Crohn's disease. A multidisciplinary approach of gastroenterologist, colorectal surgeon and radiologist is necessary for its management. A correct diagnosis, based on endoscopy, magnetic resonance imaging, endoanal ultrasound and examination under anesthesia, is crucial for perianal fistula treatment. Available medical and surgical therapies are discussed in this review, including new local treatment modalities that are under investigation.
引用
收藏
页码:1394 / 1403
页数:10
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