Enantioselective rhodium-catalysed addition of boronic acids using C2-symmetric aryl diphosphite ligands

被引：38

作者：

Chapman, CJ ^{[1
]}

Wadsworth, KJ ^{[1
]}

Frost, CG ^{[1
]}

机构：

[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2003年 / 680卷 / 1-2期

关键词：

C-C coupling; amino acids; boronic acids; rhodium; conjugate addition;

D O I：

10.1016/S0022-328X(03)00349-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The enantioselective rhodium-catalysed conjugate addition of aryl boronic acids to dehydroalanine derivatives has been successfully carried out in the presence of C-2-symmetric aryl diphosphite ligand (R,R,R-4) to prepare unnatural amino acid esters. The products have been obtained in up to 72% ee and with good isolated yield. (C) 2003 Elsevier Science B.V. All rights reserved.

引用

页码：206 / 211

页数：6

共 27 条

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BAKER MJ, 1991, CHEM COMMUN, P1292

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