Condensation of N-monosubstituted 2-naphthylamines, formaldehyde, and cyclic β-diketones. One-pot synthesis of 2,4-disubstituted derivatives of 1,2,3,4-tetrahydrobenzo[f]quinoline

被引：1

作者：

Kadutskii, A. P. ^{[1
]}

Kozlov, N. G. ^{[1
]}

机构：

[1] Natl Acad Sci Belarus, Inst Phys Organ Chem, Minsk 220072, BELARUS

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 46卷 / 09期

基金：

俄罗斯基础研究基金会;

关键词：

3-COMPONENT REACTION;

D O I：

10.1134/S1070428010090113

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various spirocyclic derivatives of 1,2,3,4-tetrahydrobenzo[f]quinoline containing substituents in the positions 2 and 4 of the ring were obtained by one-pot multicomponent condensation of available N-benzyl-2-naphthylamines, formaldehyde, and cyclic beta-diketones of cyclohexanedione series.

引用

页码：1327 / 1331

页数：5

共 14 条

[1] ALBERT A, 1949, BRIT J EXP PATHOL, V30, P159
[2] BASALAEVA LI, 2004, ZH ORG KHIM, V40, P549
[3] BERDE B, 1978, ERGOT ALKALOIDS RELA, P156
[4] CYMERMAN CJ, 1989, J MED CHEM, V32, P961, DOI DOI 10.1021/JM00125A007
[5] A novel three-component reaction of anilines, formaldehyde and dimedone: simple synthesis of spirosubstituted piperidines
Kozlov, Nikolas G.
Kadutskii, Aliaksei P.
[J]. TETRAHEDRON LETTERS, 2008, 49 (29-30) : 4560 - 4562
[6] KOZLOV NS, 1979, 5 6 BENZOKHINOLINY, P99
[7] Monge A, 1997, Drug Des Discov, V14, P291
[8] Nakanishi K., 1962, INFRARED ABSORPTION
[9] NOVGORODOVA NY, 1973, KHIM POLIM SOEDIN, V9, P191
[10] OSMANOV Z, 1977, KHIM POLIM SOEDIN, V13, P607

← 1 2 →