Melanization immune responses in mosquito vectors

被引：286
作者：
Christensen, BM
Li, JY
Chen, CC
Nappi, AJ
机构：
[1] Univ Wisconsin, Dept Anim Hlth & Biomed Sci, Madison, WI 53706 USA
[2] Univ Illinois, Dept Pathol Sci, Urbana, IL 61801 USA
[3] Natl Yang Ming Univ, Dept Parasitol, Taipei 112, Taiwan
来源：
TRENDS IN PARASITOLOGY | 2005年 / 21卷 / 04期
关键词：
D O I：
10.1016/j.pt.2005.02.007
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
The production and deposition of melanin pigments on invading pathogens and parasites represents a unique, innate immune response in the phylum Arthropoda. This immune response has started to receive considerable attention because of the potential to exploit this mechanism to control mosquito-borne diseases. In this article, we summarize knowledge about this complex biochemistry, the use of melanin biosynthesis in diverse physiological processes and the gaps in knowledge that must be addressed if this immune process is to be manipulated in genetic-based control strategies.
引用
收藏
页码：192 / 199
页数：8
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