This study aimed evaluate the feasibility of modified laparoscopic transabdominal cervicoisthmic cerclage (LTCC) and its impact on recurrent pregnancy loss (RPL) and is a retrospective observational cohort study of patients who underwent modified LTCC from 2003 to 2018 (n = 299). The surgery was performed at a mean gestational age of 12.5 weeks (range 10.5-17.5 weeks). Of the 299 patients, 190 were reported as having undergone abortion (one abortion: 91 (47.9%), two: 59 (31.1%), three or more: 40 (21.1%)) before the present pregnancy and prior to the surgery. The mean operation time was 47.4 min (range 15-100 min). We followed up with 205 of 299 patients and recorded their obstetric outcomes. There were 176 successful deliveries via cesarean section, and the fetal survival rate was 85.9% (176/205). The results of this study suggest that modified LTCC is a safe and feasible surgical option during pregnancy for patients with a history of RPL due to cervical factors.
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Univ Coll London Hosp, Womens Hlth, Elizabeth Garrett Anderson Wing,235 Euston Rd, London NW1 2BU, England
UCL, Inst Womens Hlth, 86-96 Chenies Mews, London WC1E 6HX, EnglandUniv Coll London Hosp, Womens Hlth, Elizabeth Garrett Anderson Wing,235 Euston Rd, London NW1 2BU, England
Saridogan, E.
O'Donovan, O. P.
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Univ Coll London Hosp, Womens Hlth, Elizabeth Garrett Anderson Wing,235 Euston Rd, London NW1 2BU, England
St Michaels Hosp, Southwell St, Bristol BS2 8EG, Avon, EnglandUniv Coll London Hosp, Womens Hlth, Elizabeth Garrett Anderson Wing,235 Euston Rd, London NW1 2BU, England
O'Donovan, O. P.
David, A. L.
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Univ Coll London Hosp, Womens Hlth, Elizabeth Garrett Anderson Wing,235 Euston Rd, London NW1 2BU, England
UCL, Inst Womens Hlth, 86-96 Chenies Mews, London WC1E 6HX, England
Univ Coll London Hosp, NIHR, Biomed Res Ctr, Maple House,149 Thttenham Court Rd, London W1T 7DN, EnglandUniv Coll London Hosp, Womens Hlth, Elizabeth Garrett Anderson Wing,235 Euston Rd, London NW1 2BU, England
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Grigore T Popa Univ Med & Pharm, Dept Obstet & Gynecol, Iasi 700115, RomaniaGrigore T Popa Univ Med & Pharm, Dept Obstet & Gynecol, Iasi 700115, Romania
Nemescu, Dragos
Tanasa, Ingrid Andrada
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Grigore T Popa Univ Med & Pharm, Dept Obstet & Gynecol, Iasi 700115, RomaniaGrigore T Popa Univ Med & Pharm, Dept Obstet & Gynecol, Iasi 700115, Romania
Tanasa, Ingrid Andrada
Bohiltea, Roxana Elena
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Carol Davila Univ Med & Pharm, Dept Obstet & Gynecol, 169 Splaiul Independentei, Bucharest 020021, RomaniaGrigore T Popa Univ Med & Pharm, Dept Obstet & Gynecol, Iasi 700115, Romania
Bohiltea, Roxana Elena
Coroleuca, Ciprian
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Carol Davila Univ Med & Pharm, Dept Obstet & Gynecol, 169 Splaiul Independentei, Bucharest 020021, RomaniaGrigore T Popa Univ Med & Pharm, Dept Obstet & Gynecol, Iasi 700115, Romania
Coroleuca, Ciprian
Bratila, Elvira
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Carol Davila Univ Med & Pharm, Dept Obstet & Gynecol, 169 Splaiul Independentei, Bucharest 020021, RomaniaGrigore T Popa Univ Med & Pharm, Dept Obstet & Gynecol, Iasi 700115, Romania
Bratila, Elvira
Vinturache, Angela Elena
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Queen Elizabeth II Hosp, Dept Obstet & Gynecol, Grande Prairie, AB T8V 2E8, CanadaGrigore T Popa Univ Med & Pharm, Dept Obstet & Gynecol, Iasi 700115, Romania
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West Kazakhstan Marat Ospanov Med Univ, Dept Normal Physiol, Aktobe 030000, KazakhstanWest Kazakhstan Marat Ospanov Med Univ, Dept Normal Physiol, Aktobe 030000, Kazakhstan
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West Kazakhstan Marat Ospanov Med Univ, Dept Obstet & Gynecol 2, Aktobe 030000, KazakhstanWest Kazakhstan Marat Ospanov Med Univ, Dept Normal Physiol, Aktobe 030000, Kazakhstan
Kaldygulova, Lyazzat
Amanzholkyzy, Ainur
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West Kazakhstan Marat Ospanov Med Univ, Dept Normal Physiol, Aktobe 030000, KazakhstanWest Kazakhstan Marat Ospanov Med Univ, Dept Normal Physiol, Aktobe 030000, Kazakhstan
Amanzholkyzy, Ainur
Ryzhkova, Svetlana
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West Kazakhstan Marat Ospanov Med Univ, Dept Obstet & Gynecol 2, Aktobe 030000, KazakhstanWest Kazakhstan Marat Ospanov Med Univ, Dept Normal Physiol, Aktobe 030000, Kazakhstan