Improved nickel-catalyzed cross-coupling reaction conditions between ortho-substituted aryl iodides/nonaflates and alkylzinc iodides in solution and in the solid-phase

被引:24
作者
Jensen, AE [1 ]
Dohle, W [1 ]
Knochel, P [1 ]
机构
[1] Univ Munich, Dept Chem, D-81377 Munich, Germany
关键词
nickel catalysis; cross-coupling; solid-phase; salt effect;
D O I
10.1016/S0040-4020(00)00344-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
ortho-Substituted aryl iodides and nonaflates undergo nickel-catalyzed cross-coupling reactions with functionalized alkylzinc iodides in the solid-phase as well as in solution providing high HPLC purities and good yields. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:4197 / 4201
页数:5
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